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Association between ambient air pollution a week prior to delivery and preterm birth using a nationwide study in Sweden.
Aziz, Nabeel; Stafoggia, Massimo; Stephansson, Olof; Roos, Nathalie; Kovats, Sari; Chersich, Matthew; Filippi, Veronique; Part, Cherie; Nakstad, Britt; Hajat, Shakoor; Ljungman, Petter; de Bont, Jeroen.
Afiliación
  • Aziz N; Institute of Environmental Medicine, Karolinska Institutet, Sweden.
  • Stafoggia M; Institute of Environmental Medicine, Karolinska Institutet, Sweden; Department of Epidemiology, Lazio Region Health Service, ASL Roma 1, Italy.
  • Stephansson O; Department of Women's Health, Division of Obstetrics, Karolinska University Hospital, Stockholm, Sweden; Department of Obstetrics and Gynecology, Karolinska University Hospital, Solna, Sweden.
  • Roos N; Department of Women's Health, Division of Obstetrics, Karolinska University Hospital, Stockholm, Sweden; Department of Obstetrics and Gynecology, Karolinska University Hospital, Solna, Sweden.
  • Kovats S; Department of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, UK.
  • Chersich M; Wits Reproductive Health and HIV Institute, Faculty of Health Science, University of the Witwatersrand, South Africa.
  • Filippi V; Department of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, UK; Faculty of Epidemiology and Population Health, Department of Infectious Diseases (International Health), Maternal and Newborn Health Group, LSHTM, UK.
  • Part C; Department of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, UK.
  • Nakstad B; Department of Paediatric and Adolescent Health, University of Botswana, Botswana; Division of Paediatric and Adolescent Medicine, Institute of Clinical Medicine, University of Oslo, Norway.
  • Hajat S; Department of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, UK.
  • Ljungman P; Institute of Environmental Medicine, Karolinska Institutet, Sweden; Department of Cardiology, Danderyd Hospital, Sweden.
  • de Bont J; Institute of Environmental Medicine, Karolinska Institutet, Sweden. Electronic address: jeroen.de.bont@ki.se.
Int J Hyg Environ Health ; 262: 114443, 2024 Sep.
Article en En | MEDLINE | ID: mdl-39159527
ABSTRACT

BACKGROUND:

Air pollution exposure has been linked with increased risk of preterm birth, which is one of the leading causes of infant mortality. Limited studies have attempted to explore these associations in low-polluted areas. In this study, we aimed to assess the association between short-term exposure to ambient air pollution and preterm birth in Sweden.

METHOD:

In this population-based study we included preterm births between 2014 and 2019 from the Swedish Pregnancy Register. We applied a spatiotemporal model to estimate daily levels of particulate matter <2.5 µm (PM2.5), PM < 10 µm (PM10), nitrogen dioxide (NO2), and ozone (O3) at the residential address of each participant. We applied a time-stratified case-crossover design with conditional logistic regression analysis to estimate odds ratios (OR) of preterm birth per 10 µg/m3 (PM10, NO2, O3) and 5 µg/m3 (PM2.5) increase in air pollution exposure at 0-6-day lag. Two-pollutant models were applied to evaluate the independent association of each exposure on preterm birth. We also stratified by maternal characteristics to identify potential effect modifiers.

RESULTS:

28,216 (4.5%) preterm births were included. An increase in O3 exposure was associated with increased odds of preterm birth [OR = 1.06 per 10 µg/m3 (95% CI, 1.02; 1.10]. PM2.5 and PM10 were not significantly associated with preterm birth, and NO2 displayed a negative nonlinear association with preterm birth. We did not observe any notable effect modification, but we found suggestive larger associations between O3 and preterm birth when stratifying by male sex, spontaneous delivery, and spring season.

CONCLUSIONS:

Increased O3 exposure one week before delivery was associated with an increased risk of preterm birth in Sweden, a country with levels of air pollution below the current World Health Organization air quality guidelines. Increases in O3 levels with climate change make these findings especially concerning.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ozono / Nacimiento Prematuro / Contaminantes Atmosféricos / Contaminación del Aire / Material Particulado / Dióxido de Nitrógeno Límite: Adult / Female / Humans / Male / Newborn / Pregnancy País/Región como asunto: Europa Idioma: En Revista: Int J Hyg Environ Health Asunto de la revista: SAUDE AMBIENTAL / SAUDE PUBLICA Año: 2024 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Alemania
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ozono / Nacimiento Prematuro / Contaminantes Atmosféricos / Contaminación del Aire / Material Particulado / Dióxido de Nitrógeno Límite: Adult / Female / Humans / Male / Newborn / Pregnancy País/Región como asunto: Europa Idioma: En Revista: Int J Hyg Environ Health Asunto de la revista: SAUDE AMBIENTAL / SAUDE PUBLICA Año: 2024 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Alemania