Validation of a simple isotopic technique for the measurement of global and separated renal function.
Uremia Invest
; 9(2): 177-9, 1985.
Article
en En
| MEDLINE
| ID: mdl-3915921
Schlegel and Gates described an isotopic method for the measurement of global and separated glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) based on the determination by scintillation camera of the fraction of the injected dose (99mTc-DTPA-[131I]hippuran) present in the kidneys 1-3 min after its administration. This method requires counting of the injected dose and attenuation correction, but no blood or urine sampling. We validated this technique by the simultaneous infusion of inulin and polycyclic aromatic hydrocarbon (PAH) in patients with various levels of renal function (anuric to normal). To better define individual renal function we studied 9 kidneys in patients either nephrectomized or with a nephrostomy enabling separated function measurement. A good correlation between inulin, PAH clearance, and isotopic GFR-ERPF measurement for both global and separate renal function was observed.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Renografía por Radioisótopo
/
Riñón
/
Enfermedades Renales
Límite:
Humans
Idioma:
En
Revista:
Uremia Invest
Asunto de la revista:
NEFROLOGIA
Año:
1985
Tipo del documento:
Article
Pais de publicación:
Estados Unidos