Your browser doesn't support javascript.
loading
Cerebral microbleeds in acute ischemic stroke after intravenous thrombolysis and their impact on short term outcome of stroke.
Oraby, Mohammed I; Gomaa, Rana; Abdel-Aal, Ahmed A; Hussein, Mona.
Afiliación
  • Oraby MI; Neurology Department, Beni-Suef University, Beni-Suef, Egypt.
  • Gomaa R; Neurology Department, Beni-Suef University, Beni-Suef, Egypt.
  • Abdel-Aal AA; Radiology Department, Beni-Suef University, Beni-Suef, Egypt.
  • Hussein M; Neurology Department, Beni-Suef University, Beni-Suef, Egypt.
Int J Neurosci ; : 1-9, 2024 Aug 23.
Article en En | MEDLINE | ID: mdl-39159153
ABSTRACT

OBJECTIVES:

Strong evidence suggests the occurrence of cerebral microbleeds (CMBs) in 5-13% of stroke patients within the first week after stroke onset. The aim of this work was to study risk factors associated with occurrence of CMBs in patients with stroke who received intravenous thrombolysis, and to clarify their impact on the clinical outcome.

METHODS:

This prospective observational study was conducted on 61 acute ischemic stroke patients eligible for treatment with recombinant tissue plasminogen activator (rt-PA). Assessment of stroke-related neurologic deficit was done using National Institute of Health Stroke Scale (NIHSS). Assessment of stroke related disability after 3 months from stroke onset was done using Modified Rankin Scale (mRS). CMBs were detected by T2*-weighed gradient-recalled echo (T2*-GRE) and susceptibility-weighted imaging (SWI) magnetic resonance imaging (MRI) sequences.

RESULTS:

There was a statistically significant impact of age, mean arterial pressure (MAP) at stroke onset, history of hypertension (HTN), and white matter changes assessed by Fazekas scale on the occurrence of CMBs in the included stroke patients (P-value= 0.002, <0.001, <0.001, 0.008 respectively). There was no statistically significant difference between patients with favorable and those with unfavorable outcome regarding the total number of CMBs (P-value =0.542). There was also no statistically significant difference between patients who developed complications from rt-PA and those who didn't develop regarding the total number of CMBs (P-value =0.186).

CONCLUSION:

Cerebral microbleeds are more likely to occur in older stroke patients and in those who had high MAP at stroke onset, history of HTN, and white matter changes.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Neurosci Año: 2024 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Neurosci Año: 2024 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Reino Unido