Your browser doesn't support javascript.
loading
Simultaneous detection of tyrosine and uric acid in sweat using CoWO4@CNT with a hydrogel modified electrochemical biosensor.
Zeng, Xin; Li, Xuheng; Zhang, Yong; Wang, Cuncun; Liu, Yiyi; Hou, Changjun; Huo, Danqun.
Afiliación
  • Zeng X; Key Laboratory for Biological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing 400044, PR China. houcj@cqu.edu.cn.
  • Li X; Key Laboratory for Biological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing 400044, PR China. houcj@cqu.edu.cn.
  • Zhang Y; Key Laboratory for Biological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing 400044, PR China. houcj@cqu.edu.cn.
  • Wang C; Key Laboratory for Biological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing 400044, PR China. houcj@cqu.edu.cn.
  • Liu Y; Key Laboratory for Biological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing 400044, PR China. houcj@cqu.edu.cn.
  • Hou C; Key Laboratory for Biological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing 400044, PR China. houcj@cqu.edu.cn.
  • Huo D; Chongqing Key Laboratory of Bio-perception & Intelligent Information Processing, School of Microelectronics and Communication Engineering, Chongqing University, Chongqing, 400044, PR China.
Anal Methods ; 16(34): 5902-5908, 2024 Aug 29.
Article en En | MEDLINE | ID: mdl-39158376
ABSTRACT
The levels of uric acid (UA) and tyrosine (Tyr) in sweat reflect a person's overall health. However, simultaneously identifying several components in sweat remains challenging. Here, we achieve simultaneous detection of UA and Tyr by synthesizing CoWO4@CNT in a single step using a hydrothermal method. CoWO4's high catalytic efficacy and large CNT reaction area allow the detection of 1-1000 µM UA (LOD = 0.14 µM) and 5-1000 µM Tyr (LOD = 4.2 µM). To increase sweat collection, we developed a polydopamine-polyacrylamide (PDA-PAM) hydrogel with a sweat absorption rate of up to 226%. Finally, by monitoring sweat at various times of day, our sensors can discriminate between UA and Tyr in real sweat, and the results are consistent with the individuals' activity levels. Overall, the effective electrocatalytically active materials and PDA-PAM hydrogel improve the detection of UA and Tyr. The remarkable performance of CoWO4@CNT in real samples shows that it has the potential to improve health detection and real-time sweat analysis.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sudor / Tirosina / Ácido Úrico / Técnicas Biosensibles / Hidrogeles / Técnicas Electroquímicas Límite: Humans Idioma: En Revista: Anal Methods Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sudor / Tirosina / Ácido Úrico / Técnicas Biosensibles / Hidrogeles / Técnicas Electroquímicas Límite: Humans Idioma: En Revista: Anal Methods Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido