Your browser doesn't support javascript.
loading
Imparting of Nearly Superparamagnetic Properties to Cryogel Scaffolds With Mesoporous MNPs for Magneto-Sensitive Tissue Engineering Strategies.
Demir, Didem; Ulusal, Fatma; Ulusal, Hasan; Ceylan, Seda; Dagli, Sibel; Özdemir, Nalan; Tarakçioglu, Mehmet.
Afiliación
  • Demir D; Department of Chemistry and Chemical Process Technologies, Vocational School of Technical Sciences at Mersin Tarsus Organized Industrial Zone, Tarsus University, Mersin, Turkey.
  • Ulusal F; Department of Chemistry and Chemical Process Technologies, Vocational School of Technical Sciences at Mersin Tarsus Organized Industrial Zone, Tarsus University, Mersin, Turkey.
  • Ulusal H; Department of Medical Biochemistry, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey.
  • Ceylan S; Department of Bioengineering, Faculty of Engineering, Adana Alparslan Türkes Science and Technology University, Adana, Turkey.
  • Dagli S; Department of Medical Microbiology, Faculty of Medicine, Hatay Mustafa Kemal University, Antakya, Turkey.
  • Özdemir N; Chemistry Department, Faculty of Science, Erciyes University, Kayseri, Turkey.
  • Tarakçioglu M; Department of Medical Biochemistry, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey.
Biopolymers ; : e23623, 2024 Aug 19.
Article en En | MEDLINE | ID: mdl-39158278
ABSTRACT
This work reports the assembly of mesoporous iron oxide nanoparticles (meso-MNPs) with cryogel scaffolds composed of chitosan and gelatin. Meso-MNPs with a particle size ranging from 2 and 50 nm, a surface area of 140.52 m2 g-1, and a pore volume of 0.27 cm3 g-1 were synthesized on a porous SiO2 template in the presence of PEG 6000 followed by leaching of SiO2. Different ratios of meso-MNPs were successfully incorporated into chitosangelatin cryogels up to an amount equivalent to the entire amount of polymer. The morphological structure and physicochemical properties of the cryogels were directly affected by the amount of MNPs. VSM curves showed that all composite cryogels could be magnetized by applying a magnetic field. In the context of the safety of magnetic cryogel scaffolds for use in biomedicine, it is important to note that all values are below the exposure limit for static magnetic fields, and according to cytotoxicity data, scaffolds containing meso-MNPs showed nontoxicity with cell viability ranging from 150% to 275%. In addition, microbial analysis with gram-negative and gram-positive bacteria showed that the scaffolds exhibited activity against these bacteria.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Biopolymers Año: 2024 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Biopolymers Año: 2024 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos