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The Effect of Progesterone Elevation on the Day of Trigger Administration: A Review of the Literature.
Jreij, Chris; Halimeh, Rawad; Fadel, Doha; Chamoun, Perla; Nassar, Jean; Saab, Wael; Seshadri, Srividya; Bersaoui, Marianne.
Afiliación
  • Jreij C; Faculty of Medicine, University of Balamand, Beirut, Lebanon.
  • Halimeh R; The Centre for Reproductive and Genetic Health, London, United Kingdom.
  • Fadel D; Faculty of Medicine, University of Balamand, Beirut, Lebanon.
  • Chamoun P; Faculty of Medicine, University of Balamand, Beirut, Lebanon.
  • Nassar J; Faculty of Medicine, University of Balamand, Beirut, Lebanon.
  • Saab W; Department of Obstetrics and Gynecology, Saint George Hospital University Medical Center, Beirut, Lebanon.
  • Seshadri S; The Centre for Reproductive and Genetic Health, London, United Kingdom.
  • Bersaoui M; The Centre for Reproductive and Genetic Health, London, United Kingdom.
J Reprod Infertil ; 25(2): 102-109, 2024.
Article en En | MEDLINE | ID: mdl-39157800
ABSTRACT
Since the advent of assisted reproductive technology, different variables have been shown to affect pregnancy outcomes. One of the most prevalent studied events is the premature rise in serum progesterone concentrations on the day of trigger administration during cycles of ovarian stimulation. This phenomenon, classically known as premature luteinization, has been observed significantly for decades and has been linked to adverse pregnancy outcomes and lower live birth rates. Ultimately, a quest to find a precise serum progesterone concentration cut-off value that can be effectively used to predict pregnancy outcomes prior to trigger administration is still underway. The purpose of the current research was to study the available literature on the relationship between serum progesterone on the day of trigger administration in controlled ovarian stimulation cycles used for IVF in an attempt to identify a cut-off serum progesterone concentration that can be used to effectively predict future pregnancy outcomes in fresh transfers. This study is a review of the literature and is based on information and data gathered from 36 published articles. The majority of the literature shows that a serum progesterone concentration cut-off of 1.5 ng/ml (4.77 nmol/L) can be used prior to trigger administration to effectively predict pregnancy outcomes. Premature progesterone elevation on the day or prior to the trigger administration is associated with adverse pregnancy outcomes in IVF cycles. Other factors such as follicle number, serum concentration of other hormones, and ovarian response to ovarian stimulation should also be considered to predict the success of IVF protocols.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Reprod Infertil Año: 2024 Tipo del documento: Article País de afiliación: Líbano Pais de publicación: Irán
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Reprod Infertil Año: 2024 Tipo del documento: Article País de afiliación: Líbano Pais de publicación: Irán