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Idiopathic Subglottic Stenosis in Non-Caucasian Women.
Suk, Amber; Dehom, Salem; Punjabi, Nihal; Young, VyVy N; Krishna, Priya D; Reder, Lindsay; O'Dell, Karla; Gochman, Grant E; Simmons, Ethan; Verma, Sunil P; Harmon, Matthew; Weissbrod, Philip A; Yang, Jin; Tamares, Shanalee; Crawley, Brianna K.
Afiliación
  • Suk A; School of Medicine Loma Linda University Loma Linda California USA.
  • Dehom S; School of Nursing Loma Linda University Loma Linda California USA.
  • Punjabi N; Department of Otolaryngology-Head and Neck Surgery Loma Linda University Loma Linda California USA.
  • Young VN; Department of Otolaryngology-Head and Neck Surgery University of California San Francisco California USA.
  • Krishna PD; Department of Otolaryngology-Head and Neck Surgery Loma Linda University Loma Linda California USA.
  • Reder L; Department of Otolaryngology-Head and Neck Surgery Kaiser Permanente Baldwin Park Los Angeles California USA.
  • O'Dell K; Department of Otolaryngology-Head and Neck Surgery University of Southern California Los Angeles California USA.
  • Gochman GE; Department of Otolaryngology-Head and Neck Surgery University of California San Francisco California USA.
  • Simmons E; School of Medicine Loma Linda University Loma Linda California USA.
  • Verma SP; Department of Otolaryngology-Head and Neck Surgery University of California Irvine Orange California USA.
  • Harmon M; Department of Surgery, Division of Otolaryngology-Head and Neck Surgery University of California San Diego San Diego California USA.
  • Weissbrod PA; Department of Surgery, Division of Otolaryngology-Head and Neck Surgery University of California San Diego San Diego California USA.
  • Yang J; Department of Otolaryngology-Head and Neck Surgery Loma Linda University Loma Linda California USA.
  • Tamares S; University Libraries, Loma Linda University Loma Linda California USA.
  • Crawley BK; Department of Otolaryngology-Head and Neck Surgery Loma Linda University Loma Linda California USA.
OTO Open ; 8(3): e180, 2024.
Article en En | MEDLINE | ID: mdl-39157741
ABSTRACT

Objective:

To characterize presentation, disease course, and treatment of idiopathic subglottic stenosis (iSGS) in non-Caucasian women and compare this cohort to the predominantly female, Caucasian patient cohorts identified in the literature. Study

Design:

Retrospective review. Results are compared to systematic review of demographics.

Setting:

Multiple California institutions from 2008 to 2021.

Methods:

Patients with intubation within 2 years of disease or who met exclusion criteria listed in prior publications were excluded. A systematic review of iSGS patient demographics was also completed for comparison.

Results:

Of 421 patients with iSGS, 58 self-identified as non-Caucasian women, with 50 ultimately included. Mean age of onset was 45.1 years old (95% confidence interval [CI], 41.5-48.8), and mean age at diagnosis was 47.2 years (95% CI, 43.6-50.7). Mean Charlson comorbidity index was 1.06 (n = 49, 95% CI, 0.69-1.44). At diagnosis, Cotton-Meyer severity scores (documented in n = 45) were Cotton-Myer (CM) I (28.9%), CM II (40%), and CM III (31.1%). Mean age at first endoscopic surgery was 47.7 (95% CI, 44.2-51.3) years. 64% experienced disease recurrence with a median of 11 months between their first and second surgery. Our systematic review identified 60 studies that reported demographic features in patients with iSGS. 95% of pooled patients were Caucasian, while other demographic features were similar to the current cohort.

Conclusion:

The non-Caucasian population, almost 14% of this Californian cohort, does not differ from the majority Caucasian population detailed in contemporary literature. This cohort supports the presence of some racial and ethnic heterogeneity in this disease population.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: OTO Open Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: OTO Open Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos