Your browser doesn't support javascript.
loading
Osteoporosis Treatment and Outcomes in Patients Undergoing Adult Spinal Deformity Surgery.
Shen, Thomas; Shahzad, Hania; Sierra, Frank; Wick, Joseph B; Pina, Dagoberto; Van, Benjamin W; Vander Voort, Wyatt D; Kong, Shana; Javidan, Yashar; Roberto, Rolando F; Klineberg, Eric O; Le, Hai V.
Afiliación
  • Shen T; Department of Orthopaedic Surgery, Davis, University of California, Sacramento, California, USA.
  • Shahzad H; Department of Orthopaedic Surgery, Davis, University of California, Sacramento, California, USA.
  • Sierra F; Davis School of Medicine, University of California, Sacramento, California, USA.
  • Wick JB; Department of Orthopaedic Surgery, Davis, University of California, Sacramento, California, USA.
  • Pina D; Department of Orthopaedic Surgery, Davis, University of California, Sacramento, California, USA.
  • Van BW; Department of Orthopaedic Surgery, Davis, University of California, Sacramento, California, USA.
  • Vander Voort WD; Department of Orthopaedic Surgery, Davis, University of California, Sacramento, California, USA.
  • Kong S; Department of Orthopaedic Surgery, Davis, University of California, Sacramento, California, USA.
  • Javidan Y; Department of Orthopaedic Surgery, Davis, University of California, Sacramento, California, USA.
  • Roberto RF; Department of Orthopaedic Surgery, Davis, University of California, Sacramento, California, USA.
  • Klineberg EO; Department of Orthopaedic Surgery, Davis, University of California, Sacramento, California, USA.
  • Le HV; Department of Orthopaedic Surgery, Davis, University of California, Sacramento, California, USA. Electronic address: haile@ucdavis.edu.
World Neurosurg ; 190: e1018-e1024, 2024 Oct.
Article en En | MEDLINE | ID: mdl-39154959
ABSTRACT

BACKGROUND:

This study aims to evaluate the prevalence and treatment of osteoporosis in patients undergoing long spinal fusion for adult spinal deformity (ASD) and compare the impact of osteoporosis treatment on surgical and radiographic outcomes.

METHODS:

We conducted a retrospective study of adult patients aged ≥40 years who underwent thoracolumbar ASD surgery at a single academic center between 2015 and 2021. We recorded demographic information, procedural details, and pharmacologic treatments. Primary outcomes included preoperative and postoperative sagittal vertical axis, pelvic incidence-lumbar lordosis mismatch, and postoperative complications such as surgical site infection, pseudarthrosis, proximal junctional kyphosis (PJK), and proximal junctional failure. Patients with osteoporosis were compared to those without.

RESULTS:

Among 168 patients, the prevalence of osteoporosis was 28.6%. Osteoporotic patients were older and predominantly female. At the time of surgery, 70.8% of osteoporotic patients were receiving pharmacologic treatment. Preoperative pelvic incidence-lumbar lordosis mismatch and sagittal vertical axis did not differ significantly between osteoporotic and nonosteoporotic cohorts. Both cohorts showed similar postoperative improvements. The osteoporotic cohort had a higher rate of PJK (35.4% vs. 17.5%, p=0.01), but no significant difference in proximal junctional failure rates. No significant differences were found between monotherapy and combination therapy outcomes for osteoporotic patients.

CONCLUSIONS:

Osteoporotic patients undergoing ASD surgery exhibited similar surgical outcomes and alignment improvements compared to nonosteoporotic patients, despite a higher rate of PJK. Pharmacological treatment appears beneficial in managing osteoporosis-related surgical risks. These findings highlight the importance of identifying and treating osteoporosis in ASD patients to minimize complications.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoporosis / Complicaciones Posoperatorias / Fusión Vertebral Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: World Neurosurg Asunto de la revista: NEUROCIRURGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoporosis / Complicaciones Posoperatorias / Fusión Vertebral Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: World Neurosurg Asunto de la revista: NEUROCIRURGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos