Association between frailty and main work during the LIFE: A cross-sectional analysis of the UK Biobank.
Exp Gerontol
; 195: 112548, 2024 Oct 01.
Article
en En
| MEDLINE
| ID: mdl-39153414
ABSTRACT
BACKGROUND:
The role of main work during the life course in predicting frailty, a typical geriatric syndrome, is still largely unknown. Therefore, with this research, we aimed to investigate the potential association between the main work done during the life with frailty and pre-frailty among participants 60 years and older of the UK Biobank study.METHODS:
Frailty and pre-frailty presence were ascertained using a model including 5 indicators (weakness, slowness, weight loss, low physical activity, and exhaustion); the main employment status was ascertained using self-reported information. The association between frailty and main work was explored using an ordinal logistic regression model and reported as odds ratios (ORs) with their 95 % confidence intervals (CIs).RESULTS:
The final sample comprised a total of 50,447 individuals (mean age 64.2 years, females 50.2 %). Individuals with higher qualifications had a reduced risk of frailty (OR = 0.881, 95%CI = 0.83-0.95, p-value<0.001 for pre-frail and OR = 0.681, 95%CI = 0.63-0.73, p-value<0.001 for frail) compared to those with lower qualifications. Moreover, active participation in the workforce, compared to being inactive, emerged as a protective factor from frailty (OR = 0.753, 95%CI = 0.70-0.81, p-value<0.001). The categories of Associate Professional and Technical Occupations exhibited protective effects against both pre-frailty and frailty. Similarly, occupations categorized as Professional and Management demonstrated protective effects against pre-frailty and frailty when compared to Elementary Occupations. Additionally, engagement in Trades and Services occupations, as opposed to Elementary Occupations, appeared to be protective against frailty.CONCLUSIONS:
In this large cross-sectional investigation based on the data of the UK Biobank we found that work during lifetime could be an important factor in determining frailty later in life.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Anciano Frágil
/
Bancos de Muestras Biológicas
/
Fragilidad
Límite:
Aged
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Female
/
Humans
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Male
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Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Exp Gerontol
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Reino Unido