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The Glymphatic System and its Relationship to Migraine.
Burgos, Alana Fretes; Olson, Patricia A; Vgontzas, Angeliki.
Afiliación
  • Burgos AF; Department of Neurology, Tufts Medical Center, Boston, MA, USA.
  • Olson PA; Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Vgontzas A; Graham Headache Center, Department of Neurology, Brigham and Women's Faulkner Hospital, Harvard Medical School, 1153 Centre Street Suite 4H, Boston, MA, 02130, USA. avgontzas@bwh.harvard.edu.
Curr Neurol Neurosci Rep ; 2024 Aug 16.
Article en En | MEDLINE | ID: mdl-39150650
ABSTRACT
PURPOSE OF REVIEW We aim to critically review animal and human studies of the glymphatic system in migraine and propose a model for how the glymphatic system may function in migraine, based on the available evidence. RECENT

FINDINGS:

Early studies in animal models report migraine attacks temporarily disrupt glymphatic flow. Human imaging studies suggest chronic migraine may be associated with alterations in glymphatic system function, albeit with conflicting results. Presently, it remains unknown whether repetitive migraine attacks or frequent nights of insomnia impair glymphatic system function over time in those with migraine, and whether alterations in glymphatic function could contribute to worsening migraine disability or risk for cognitive disease. Longitudinal studies of glymphatic function in patients with migraine and insomnia, with inclusion of cognitive assessments, may be informative.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Curr Neurol Neurosci Rep Asunto de la revista: NEUROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Curr Neurol Neurosci Rep Asunto de la revista: NEUROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos