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Clinical Outcomes of Excisional Goniotomy with the Kahook Dual Blade: 6-Year Results.
Vasu, Pranav; Abubaker, Yazan; Boopathiraj, Nithya; Wagner, Isabella V; Lentz, P Connor; Dorairaj, Emily; Shokair, Aya; Qozat, Ibrahim; Miller, Darby D; Dorairaj, Syril.
Afiliación
  • Vasu P; Department of Medicine, Creighton University School of Medicine, Phoenix, AZ, USA.
  • Abubaker Y; Department of Ophthalmology, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL, USA.
  • Boopathiraj N; Department of Ophthalmology, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL, USA.
  • Wagner IV; Department of Ophthalmology, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL, USA.
  • Lentz PC; Department of Ophthalmology, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL, USA.
  • Dorairaj E; Department of Ophthalmology, Mayo Clinic Alix School of Medicine, Jacksonville, FL, USA.
  • Shokair A; Department of Medicine, Charles E. Schmidt College of Medicine, Boca Raton, FL, USA.
  • Qozat I; Department of Medicine, University of California Riverside School of Medicine, Riverside, CA, USA.
  • Miller DD; Department of Ophthalmology, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL, USA.
  • Dorairaj S; Department of Ophthalmology, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL, USA.
Ophthalmol Ther ; 13(10): 2731-2744, 2024 Oct.
Article en En | MEDLINE | ID: mdl-39150602
ABSTRACT

INTRODUCTION:

This study aims to evaluate the long-term clinical outcomes of excisional goniotomy with the Kahook Dual Blade (KDB) in the management of various types of glaucoma.

METHODS:

This was a retrospective, noncomparative chart review of 90 eyes of 53 patients with glaucoma that underwent standalone KDB goniotomy (KDB-alone group) or KDB goniotomy with concomitant phacoemulsification (KDB-phaco group) between October 2015 and October 2017. Surgical success was defined as an intraocular pressure (IOP) reduction by ≥ 20% at the last follow-up with no surgical reinterventions required and a final IOP ≥ 4 mmHg and ≤ 21 mmHg. We also report on changes from baseline in IOP, number of glaucoma medications, best-corrected visual acuity (BCVA), and visual field parameters, for up to 72 months.

RESULTS:

At 72 months, mean (standard deviation [SD]) IOP was reduced from 17.5 (5.7) to 13.6 (3.0) mmHg (P < 0.0001) in the KDB-phaco group and from 23.3 (5.9) to 15.1 (6.2) mmHg (P = 0.0593) in the KDB-alone group. The mean (SD) number of glaucoma medications was reduced from 1.3 (1.0) to 0.8 (0.9) (P < 0.0001) in the KDB-phaco group and from 1.2 (1.0) to 0.7 (0.8) (P = 0.3409) in the KDB-alone group. During the 72-month follow-up, surgical success was achieved in 24 of the 52 available eyes (46.2%). Four eyes underwent a glaucoma surgical reintervention by 72 months.

CONCLUSIONS:

Excisional goniotomy with the KDB effectively lowered the IOP (by an average of 28.0% from baseline) and maintained or further reduced glaucoma medication burdens (by an average of 30.8% from baseline) under an excellent safety profile, independent of phacoemulsification status. The procedure exhibited favorable success for up to 6 years, providing valuable insights into its long-term efficacy as a glaucoma treatment.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Ophthalmol Ther Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Ophthalmol Ther Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido