Your browser doesn't support javascript.
loading
Updated joint ESPGHAN/NASPGHAN guidelines for management of Helicobacter pylori infection in children and adolescents (2023).
Homan, Matjaz; Jones, Nicola L; Bontems, Patrick; Carroll, Matthew W; Czinn, Steven J; Gold, Benjamin D; Goodman, Karen; Harris, Paul R; Jerris, Robert; Kalach, Nicolas; Kori, Michal; Megraud, Francis; Rowland, Marion; Tavares, Marta.
Afiliación
  • Homan M; Faculty of Medicine, Children's Hospital in Ljubljana, University of Ljubljana, Ljubljana, Slovenia.
  • Jones NL; Division of Gastroenterology Hepatology and Nutrition, SickKids, University of Toronto, Toronto, Ontario, Canada.
  • Bontems P; Université Libre de Bruxelles, Hôpital Unversitaire des Enfants Reine Fabiola, Hôpitaux Universitaires de Bruxelles, Brussels, Belgium.
  • Carroll MW; Division of Gastroenterology and Nutrition, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
  • Czinn SJ; University of Maryland School of Medicine, Baltimore, Maryland, USA.
  • Gold BD; GI Care for Kids, LLC, Children's Center for Digestive Healthcare LLC, Children's Healthcare of Atlanta, Atlanta, Georgia, USA.
  • Goodman K; Faculty of Medicine and Dentistry, Division of Gastroenterology, University of Alberta, Edmonton, Alberta, Canada.
  • Harris PR; Department of Pediatric Gastroenterology and Nutrition, Pontificia Universidad Catolica de Chile, Santiago, Chile.
  • Jerris R; Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Kalach N; Department of Pediatrics, Saint Vincent de Paul Hospital, Groupement des Hôpitaux de l'Institut Catholique de Lille (GHICL), Catholic University of Lille, Lille, France.
  • Kori M; Pediatric Gastroenterology, Kaplan Medical Center, Rehovot, and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
  • Megraud F; Inserm U1312 BRIC, Université de Bordeaux, Bordeaux, France.
  • Rowland M; School of Medicine and Medical Science, University College Dublin, Dublin, Ireland.
  • Tavares M; Unidade de Gastroenterologia, Centro Materno Infantil do Norte, Centro Hospitalar Universitário de Santo António, Porto, Portugal.
J Pediatr Gastroenterol Nutr ; 79(3): 758-785, 2024 Sep.
Article en En | MEDLINE | ID: mdl-39148213
ABSTRACT

BACKGROUND:

Evolving epidemiological data and increasing antibiotic resistance mandate an update of the European and North American Societies of Pediatric Gastroenterology, Hepatology and Nutrition guidelines.

METHODS:

Certainty of evidence and strength of recommendations were rated by experts according to the Grading of Recommendation Assessment, Development, and Evaluation approach. PICO (patient population, intervention, comparator, and outcome) questions were developed and voted on by the group. Recommendations were formulated using the Evidence to Decision framework.

RESULTS:

The current literature supports many of the previous recommendations and several new recommendations. Invasive testing with strain antimicrobial susceptibility analysis is recommended for the diagnosis and selection of eradication therapy for H. pylori infection. Molecular methods are acceptable for detection of infection and of antibiotic resistance in gastric biopsy specimens. Reliable, noninvasive tests can be used as a screening method for children with history of gastric cancer in a first-degree relative. When investigating causes of chronic immune thrombocytopenic purpura, testing for H. pylori is no longer recommended. When investigating other diseases such as inflammatory bowel disease, celiac disease, or eosinophilic esophagitis, specific diagnostic biopsies for H. pylori infection are not indicated. However, if H. pylori is an incidental finding, treatment may be considered after discussing the risks and benefits. Treatment should be based on antibiotic antimicrobial susceptibility testing and, if unavailable, regimens containing clarithromycin should be avoided.

CONCLUSIONS:

Due to decreasing prevalence of infection, increasing challenges with antibiotic resistance, and emerging evidence regarding complications of infection, clinicians must be aware of these recommended changes to appropriately manage H. pylori infection and its clinical sequelae in children.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Helicobacter pylori / Infecciones por Helicobacter / Antibacterianos Límite: Adolescent / Child / Humans Idioma: En Revista: J Pediatr Gastroenterol Nutr Año: 2024 Tipo del documento: Article País de afiliación: Eslovenia Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Helicobacter pylori / Infecciones por Helicobacter / Antibacterianos Límite: Adolescent / Child / Humans Idioma: En Revista: J Pediatr Gastroenterol Nutr Año: 2024 Tipo del documento: Article País de afiliación: Eslovenia Pais de publicación: Estados Unidos