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STress computed tomogRaphy perfusion and stress cArdiac magnetic resonance for ThE manaGement of suspected or known coronarY artery disease: resources and outcomes impact.
Baggiano, Andrea; Baessato, Francesca; Mushtaq, Saima; Annoni, Andrea Daniele; Cannata, Francesco; Carerj, Maria Ludovica; Del Torto, Alberico; Fazzari, Fabio; Formenti, Alberto; Frappampina, Antonio; Fusini, Laura; Junod, Daniele; Mancini, Maria Elisabetta; Mantegazza, Valentina; Maragna, Riccardo; Marchetti, Francesca; Sbordone, Francesco Paolo; Tassetti, Luigi; Volpe, Alessandra; Guglielmo, Marco; Rossi, Alexia; Rovera, Chiara; Rabbat, Mark G; Guaricci, Andrea Igoren; Cau, Claudio; Saba, Luca; Berna, Giovanni; Sforza, Chiarella; Pepi, Mauro; Pontone, Gianluca.
Afiliación
  • Baggiano A; Centro Cardiologico Monzino IRCCS, Milan, Italy; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
  • Baessato F; Department of Cardiology, San Maurizio Regional Hospital, Bolzano, Italy.
  • Mushtaq S; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Annoni AD; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Cannata F; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Carerj ML; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Del Torto A; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Fazzari F; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Formenti A; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Frappampina A; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Fusini L; Centro Cardiologico Monzino IRCCS, Milan, Italy; Department of Electronics, Information and Biomedical engineering, Politecnico di Milano, Milan, Italy.
  • Junod D; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Mancini ME; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Mantegazza V; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Maragna R; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Marchetti F; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Sbordone FP; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Tassetti L; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Volpe A; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Guglielmo M; Department of Cardiology, Division of Heart and Lungs, Utrecht University, Utrecht University Medical Center, Utrecht, the Netherlands; Department of Cardiology, Haga Teaching Hospital, The Hague, the Netherlands.
  • Rossi A; Department of Nuclear Medicine, University Hospital, Zurich, Switzerland; Center for Molecular Cardiology, University of Zurich, Zurich, Switzerland.
  • Rovera C; Ospedale di Chivasso, Turin, Italy.
  • Rabbat MG; Loyola University of Chicago, Chicago, IL, USA; Edward Hines Jr. VA Hospital, Hines, IL, USA.
  • Guaricci AI; University Cardiology Unit, Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Bari, Italy.
  • Cau C; Department of Medical Sciences, University of Cagliari, Cagliari, Italy.
  • Saba L; Department of Medical Sciences, University of Cagliari, Cagliari, Italy.
  • Berna G; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Sforza C; Department of Biomedical Sciences for Health, University of Milan, Milan, Italy.
  • Pepi M; Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Pontone G; Centro Cardiologico Monzino IRCCS, Milan, Italy; Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy. Electronic address: gianluca.pontone@ccfm.it.
Article en En | MEDLINE | ID: mdl-39147676
ABSTRACT

BACKGROUND:

The aim of this study is to describe resources and outcomes of coronary computed tomography angiography plus Stress CT perfusion (CCTA â€‹+ â€‹Stress-CTP) and stress cardiovascular magnetic resonance (Stress-CMR) in symptomatic patients with suspected or known CAD.

METHODS:

Six hundred and twenty-four consecutive symptomatic patients with intermediate to high-risk pretest likelihood for CAD or previous history of revascularization referred to our hospital for clinically indicated CCTA â€‹+ â€‹Stress-CTP or Stress-CMR were enrolled. Stress-CTP scans were performed in 223 patients while 401 patients performed Stress-CMR. Patient follow-up was performed at 1 year after index test performance. Endpoints were all cardiac events, as a combined endpoint of revascularization, non-fatal MI and death, and hard cardiac events, as combined endpoint of non-fatal MI and death.

RESULTS:

Twenty-nine percent of patients who underwent CCTA â€‹+ â€‹Stress-CTP received revascularization, 7% of subjects assessed with Stress-CMR were treated invasively, and a low number of non-fatal MI and death was observed with both strategies (hard events in 0.4% of patients that had CCTA â€‹+ â€‹Stress-CTP as index test, and in 3% of patients evaluated with Stress-CMR). According to the predefined endpoints, CCTA â€‹+ â€‹Stress-CTP group showed high rate of all cardiac events and low rate of hard cardiac events, respectively. The cumulative costs were 1970 â€‹± â€‹2506 Euro and 733 â€‹± â€‹1418 Euro for the CCTA â€‹+ â€‹Stress-CTP group and Stress-CMR group, respectively.

CONCLUSIONS:

The use of CCTA â€‹+ â€‹Stress-CTP strategy was associated with high referral to revascularization but with a favourable trend in terms of hard cardiac events and diagnostic yield in identifying individuals at lower risk of adverse events despite the presence of CAD.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Cardiovasc Comput Tomogr Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / RADIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Cardiovasc Comput Tomogr Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / RADIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos