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Dead space volumes in cats and dogs with small body mass ventilated with a fixed tidal volume.
Girotto, Carolina H; Ospina-Argüelles, Diego A; Teixeira-Neto, Francisco J; Assis-Vieira, Paulo V; Martins, Alessandro R C; Kerr, Carolyn.
Afiliación
  • Girotto CH; Department of Veterinary Surgery and Animal Reproduction, Faculdade de Medicina Veterinária e Zootecnia, Universidade Estadual Paulista (UNESP), Botucatu, SP, Brazil.
  • Ospina-Argüelles DA; Department of Anesthesiology, Faculdade de Medicina, Universidade Estadual Paulista (UNESP), Botucatu, SP, Brazil.
  • Teixeira-Neto FJ; Department of Veterinary Surgery and Animal Reproduction, Faculdade de Medicina Veterinária e Zootecnia, Universidade Estadual Paulista (UNESP), Botucatu, SP, Brazil; Department of Anesthesiology, Faculdade de Medicina, Universidade Estadual Paulista (UNESP), Botucatu, SP, Brazil. Electronic address
  • Assis-Vieira PV; Department of Veterinary Surgery and Animal Reproduction, Faculdade de Medicina Veterinária e Zootecnia, Universidade Estadual Paulista (UNESP), Botucatu, SP, Brazil.
  • Martins ARC; UFAPE Veterinary Intensive Care Unit, São Paulo, SP, Brazil.
  • Kerr C; Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
Vet Anaesth Analg ; 2024 Jun 28.
Article en En | MEDLINE | ID: mdl-39138051
ABSTRACT

OBJECTIVE:

To compare the portion of tidal volume (VT) ventilating dead space volumes in nonbrachycephalic cats and dogs with small body mass receiving volume-controlled ventilation (VCV) with a fixed VT. STUDY

DESIGN:

Prospective, experimental study. ANIMALS A group of eight healthy adult cats and dogs [ideal body weight (IBW) 3.0 ± 0.5 and 3.8 ± 1.1 kg, respectively].

METHODS:

Anesthetized cats and dogs received VCV with a 12 mL kg-1 VT (inspiratory pause ≥ 0.5 seconds). Respiratory rate (fR) was adjusted to maintain normocapnia. Airway dead space (VDaw) and alveolar tidal volume (VTalv) were measured by volumetric capnography. Physiological dead space (VDphys) and VDphys/VT ratio were calculated using the Bohr-Enghoff method. Data recorded before surgery were compared by an unpaired t-test or Mann-Whitney U test (p < 0.05 considered significant).

RESULTS:

The IBW (p = 0.07), PaCO2 (p = 0.40) and expired VT [VT(exp)] (p = 0.77) did not differ significantly between species. The VDaw (mL kg-1) was lower in cats (3.7 ± 0.4) than in dogs (7.7 ± 0.9) (p < 0.0001). The VTalv (mL kg-1) was larger in cats (8.3 ± 0.7) than in dogs (4.3 ± 0.7) (p < 0.0001). Cats presented a smaller VDphys/VT ratio (0.33 ± 0.03) and VDphys (4.0 ± 0.3 mL kg-1) than dogs (VDphys/VT 0.60 ± 0.09; VDphys 7.2 ± 1.4 mL kg-1) (p < 0.0001). The fR and minute ventilation (VT(exp) × fR) were lower in cats than in dogs (p = 0.048 and p = 0.038, respectively). CONCLUSIONS AND CLINICAL RELEVANCE A fixed VT results in more effective ventilation in cats than in dogs with small body mass because of species-specific differences in and VDaw and VDphys. Because of the smaller VDaw and VDphys in cats than in dogs, a lower fR is required to maintain normocapnia in cats.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Vet Anaesth Analg Asunto de la revista: ANESTESIOLOGIA / MEDICINA VETERINARIA Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Vet Anaesth Analg Asunto de la revista: ANESTESIOLOGIA / MEDICINA VETERINARIA Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos