Your browser doesn't support javascript.
loading
Editing microbes to mitigate enteric methane emissions in livestock.
Khan, Faheem Ahmed; Ali, Azhar; Wu, Di; Huang, Chunjie; Zulfiqar, Hamza; Ali, Muhammad; Ahmed, Bilal; Yousaf, Muhammad Rizwan; Putri, Ezi Masdia; Negara, Windu; Imran, Muhammad; Pandupuspitasari, Nuruliarizki Shinta.
Afiliación
  • Khan FA; Research Center for Animal Husbandry, National Research and Innovation Agency, Jakarta, 10340, Indonesia.
  • Ali A; Department of Animal Science, Faculty of Animal and Agricultural Sciences, Universitas Diponegoro, Semarang, Indonesia.
  • Wu D; Institute of Reproductive Medicine, School of Medicine, Nantong University, Nantong, 226001, China.
  • Huang C; Institute of Reproductive Medicine, School of Medicine, Nantong University, Nantong, 226001, China.
  • Zulfiqar H; Department of Animal Science, Faculty of Animal and Agricultural Sciences, Universitas Diponegoro, Semarang, Indonesia.
  • Ali M; Institute of Animal and Diary sciences, Faculty of Animal Husbandry, Agriculture University, Faisalabad, Pakistan.
  • Ahmed B; Department of Animal Science, Faculty of Animal and Agricultural Sciences, Universitas Diponegoro, Semarang, Indonesia.
  • Yousaf MR; Department of Animal Science, Faculty of Animal and Agricultural Sciences, Universitas Diponegoro, Semarang, Indonesia.
  • Putri EM; Research Center for Animal Husbandry, National Research and Innovation Agency, Jakarta, 10340, Indonesia.
  • Negara W; Research Center for Animal Husbandry, National Research and Innovation Agency, Jakarta, 10340, Indonesia.
  • Imran M; Department of Microbiology, Quaid-i-Azam University, Islamabad, Pakistan.
  • Pandupuspitasari NS; Department of Animal Science, Faculty of Animal and Agricultural Sciences, Universitas Diponegoro, Semarang, Indonesia. shin_tse@yahoo.com.
World J Microbiol Biotechnol ; 40(10): 300, 2024 Aug 13.
Article en En | MEDLINE | ID: mdl-39134917
ABSTRACT
Livestock production significantly contributes to greenhouse gas (GHG) emissions particularly methane (CH4) emissions thereby influencing climate change. To address this issue further, it is crucial to establish strategies that simultaneously increase ruminant productivity while minimizing GHG emissions, particularly from cattle, sheep, and goats. Recent advancements have revealed the potential for modulating the rumen microbial ecosystem through genetic selection to reduce methane (CH4) production, and by microbial genome editing including CRISPR/Cas9, TALENs (Transcription Activator-Like Effector Nucleases), ZFNs (Zinc Finger Nucleases), RNA interference (RNAi), Pime editing, Base editing and double-stranded break-free (DSB-free). These technologies enable precise genetic modifications, offering opportunities to enhance traits that reduce environmental impact and optimize metabolic pathways. Additionally, various nutrition-related measures have shown promise in mitigating methane emissions to varying extents. This review aims to present a future-oriented viewpoint on reducing methane emissions from ruminants by leveraging CRISPR/Cas9 technology to engineer the microbial consortia within the rumen. The ultimate objective is to develop sustainable livestock production methods that effectively decrease methane emissions, while maintaining animal health and productivity.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Rumen / Gases de Efecto Invernadero / Ganado / Sistemas CRISPR-Cas / Edición Génica / Metano Límite: Animals Idioma: En Revista: World J Microbiol Biotechnol Año: 2024 Tipo del documento: Article País de afiliación: Indonesia Pais de publicación: Alemania
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Rumen / Gases de Efecto Invernadero / Ganado / Sistemas CRISPR-Cas / Edición Génica / Metano Límite: Animals Idioma: En Revista: World J Microbiol Biotechnol Año: 2024 Tipo del documento: Article País de afiliación: Indonesia Pais de publicación: Alemania