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Genetic profiling in radiotherapy: a comprehensive review.
Rubini, Dino; Gagliardi, Federico; Menditti, Vittorio Salvatore; D'Ambrosio, Luca; Gallo, Paolo; D'Onofrio, Ida; Pisani, Antonio Rosario; Sardaro, Angela; Rubini, Giuseppe; Cappabianca, Salvatore; Nardone, Valerio; Reginelli, Alfonso.
Afiliación
  • Rubini D; Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
  • Gagliardi F; Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
  • Menditti VS; Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
  • D'Ambrosio L; Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
  • Gallo P; Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
  • D'Onofrio I; Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
  • Pisani AR; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', Bari, Italy.
  • Sardaro A; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', Bari, Italy.
  • Rubini G; Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', Bari, Italy.
  • Cappabianca S; Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
  • Nardone V; Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
  • Reginelli A; Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Front Oncol ; 14: 1337815, 2024.
Article en En | MEDLINE | ID: mdl-39132508
ABSTRACT
This comprehensive review explores the pivotal role of radiotherapy in cancer treatment, emphasizing the diverse applications of genetic profiling. The review highlights genetic markers for predicting radiation toxicity, enabling personalized treatment planning. It delves into the impact of genetic profiling on radiotherapy strategies across various cancer types, discussing research findings related to treatment response, prognosis, and therapeutic resistance. The integration of genetic profiling is shown to transform cancer treatment paradigms, offering insights into personalized radiotherapy regimens and guiding decisions in cases where standard protocols may fall short. Ultimately, the review underscores the potential of genetic profiling to enhance patient outcomes and advance precision medicine in oncology.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Oncol Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Oncol Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza