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Fluorescein Angiography Parameters in Premature Neonates.
da Cruz, Natasha F S; Hoyek, Sandra; Sengillo, Jesse D; Rodríguez, Ana; de Oliveira, Giselle; Negron, Catherin I; Patel, Nimesh A; Berrocal, Audina M.
Afiliación
  • da Cruz NFS; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.
  • Hoyek S; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts.
  • Sengillo JD; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.
  • Rodríguez A; Neonatal Intensive Care Unit, Holtz Children's Hospital, Jackson Health System, University of Miami, Miami, Florida.
  • de Oliveira G; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.
  • Negron CI; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.
  • Patel NA; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts.
  • Berrocal AM; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.
Ophthalmol Sci ; 4(6): 100561, 2024.
Article en En | MEDLINE | ID: mdl-39132023
ABSTRACT

Purpose:

To describe fluorescein angiography (FA) parameters observed in premature neonates with retinopathy of prematurity (ROP).

Design:

Retrospective case series.

Subjects:

Patients with ROP who underwent FA imaging using Retcam at Holtz Children's Hospital from November 2014 to October 2022.

Methods:

Fluorescein angiography images of the included patients were analyzed with a focus on the timing of angiography phases, including choroidal flush, retinal, and recirculation phases. Gestational age, birth weight (BW), age at imaging, treatment choice, and any FA complications were documented. Main Outcome

Measures:

Dose of fluorescein administered, onset and duration of each angiography phase, and FA findings in ROP-treated patients.

Results:

A total of 72 images of 72 eyes were reviewed. Image quality was deemed suitable for inclusion in 64 eyes (88.9%) of 43 patients. The mean gestational age and BW at birth were 24.4 ± 1.9 weeks and 607.8 ± 141.3 g, respectively. The mean postmenstrual age at FA imaging was 50.5 ± 40.8 weeks. All eyes (100%) received treatment with intravitreal injection of anti-VEGF at a mean age of 35.5 ± 2.4 weeks. The onset and duration of angiography phases were relatively variable within the cohort. Choroidal flush occurred at a mean time of 12.2 seconds (range 6-22 seconds). A subsequent retinal phase was documented at a mean time of 11.96 seconds (range 3-22 seconds). Recirculation phase was complete at an average time of 2.15 minutes (range 1-5.45 minutes) postfluorescein injection. None of patients developed allergic reactions to fluorescein injection, such as rash, respiratory distress, tachycardia, fever, or local injection site reactions.

Conclusions:

Angiographic phases on FA in preterm infants with ROP are variable and may occur earlier than the established references for adults. Financial Disclosures Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Ophthalmol Sci Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Ophthalmol Sci Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos