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Systemic Mastocytosis Imitating Eosinophilic Enterocolitis.
Muller, Tamlynn Lynette; Van Der Merwe, Kevin; Steele, Chris; Papanikolaou, Maria; O'Dowd, Gerry; Parihar, Vikrant.
Afiliación
  • Muller TL; Department of Internal Medicine, Letterkenny University Hospital, Letterkenny Co. Donegal, Ireland.
  • Van Der Merwe K; Department of Internal Medicine, Letterkenny University Hospital, Letterkenny Co. Donegal, Ireland.
  • Steele C; Department of Gastroenterology, Letterkenny University Hospital, Letterkenny Co. Donegal, Ireland.
  • Papanikolaou M; Department of Haematology, Letterkenny University Hospital, Letterkenny Co. Donegal, Ireland.
  • O'Dowd G; Department of Histopathology, Letterkenny University Hospital, Letterkenny Co. Donegal, Ireland.
  • Parihar V; Department of Gastroenterology, Letterkenny University Hospital, Letterkenny Co. Donegal, Ireland.
Gastro Hep Adv ; 1(3): 417-419, 2022.
Article en En | MEDLINE | ID: mdl-39131682
ABSTRACT
Eosinophilic gastrointestinal disorders produce gastrointestinal dysfunction as eosinophils accumulate throughout gastrointestinal tissues. The majority of eosinophilic gastrointestinal disorders are a diagnosis of exclusion, and a magnitude of differentials must be considered. A history of anaphylaxis raises the suspicion that systemic mastocytosis (SM) is the foremost differential to be considered. SM (hematological neoplasm) is characterized by the accumulation of clonal mast cells in systemic tissues that causes gastrointestinal manifestations. In these rare cases, serum tryptase and tissue staining for c-kit/CD117 (an immunohistochemical marker of mast cells) will clinch the diagnosis. Gastrointestinal manifestations of SM are expeditiously resolved with combined oral antihistamines.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Gastro Hep Adv Año: 2022 Tipo del documento: Article País de afiliación: Irlanda Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Gastro Hep Adv Año: 2022 Tipo del documento: Article País de afiliación: Irlanda Pais de publicación: Países Bajos