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Solitary Intraosseous Myofibroma of the Mandible in a Nine-Year-Old Child: A Case Report and Literature Review.
Lazim, Ahmed; Amer, Samir M; Eltawil, Ghadir M; Laski, Robert; Kuklani, Riya.
Afiliación
  • Lazim A; Pathology, Temple University Hospital, Philadelphia, USA.
  • Amer SM; Pathology, Temple University Hospital, Philadelphia, USA.
  • Eltawil GM; Dentistry, Al Hokail Specialized Digital Polyclinics Academy, Muharraq, BHR.
  • Laski R; Oral Surgery, Valley Oral Surgery, Allentown, USA.
  • Kuklani R; Pathology, Temple University Hospital, Philadelphia, USA.
Cureus ; 16(7): e64232, 2024 Jul.
Article en En | MEDLINE | ID: mdl-39130873
ABSTRACT
Myofibroma (MF) is a benign neoplasm derived from myofibroblasts. While they are infrequent, these tumors are predominantly found in the pediatric group and seldom manifest as intraosseous mandibular tumors. Herein, we present a 9-year-old female with a radiolucent lesion in the left mandible associated with malposed left lower canine and 1st premolar teeth. Clinical examination revealed a slightly tender 5×4 cm firm mass resulting in an expansion of the buccal and lingual aspects of the mandible in the canine and first premolar region. An incisional biopsy revealed a benign tumor consisting of spindle cells organized in fascicles, alongside dispersed thin-walled blood vessels. Tumor cells tested positive for α-smooth muscle actin (SMA) and vimentin. Given these findings, a diagnosis of MF was established. To the best of our knowledge, only 45 cases of solitary MF of the mandible have been reported in the pediatric age group in the literature. We describe one additional case and provide a review of the literature.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos