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Exploring the Therapeutic Potential of Lenvatinib: A Complete Pathological Response in an Operable Case of Hepatocellular Carcinoma.
Goyal, Vipul; Muralee, Madhu; Raveendran, Subhash; K, Chandramohan; T M, Anoop.
Afiliación
  • Goyal V; Surgical Oncology, Regional Cancer Centre, Thiruvananthapuram, IND.
  • Muralee M; Surgical Oncology, Regional Cancer Centre, Thiruvananthapuram, IND.
  • Raveendran S; Surgical Oncology, Regional Cancer Centre, Thiruvananthapuram, IND.
  • K C; Surgical Oncology, Regional Cancer Centre, Thiruvananthapuram, IND.
  • T M A; Medical Oncology, Regional Cancer Centre, Thiruvananthapuram, IND.
Cureus ; 16(7): e64166, 2024 Jul.
Article en En | MEDLINE | ID: mdl-39119429
ABSTRACT
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, with increasing incidence and mortality rates. This case report presents a unique instance of a 66-year-old male patient with operable HCC who achieved a complete pathological response after short-term preoperative treatment with lenvatinib. The patient, with a history of diabetes and hypertension, was diagnosed with HCC and started on lenvatinib due to logistical reasons. Despite discontinuing the treatment after one week due to altered sensorium, a significant reduction in tumor size was observed. The patient underwent successful surgery, and the final histopathology report indicated a complete pathological response. This case highlights the potential of lenvatinib as a therapeutic option in the management of HCC, even in operable cases, and opens avenues for further research into its efficacy and applicability.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos