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Assessing the HIV care continuum among transgender women during 11 years of follow-up: results from the Netherlands' ATHENA observational cohort.
Jongen, Vita W; Daans, Ceranza; van Sighem, Ard; Schim van der Loeff, Maarten; Hage, Kris; Welling, Camiel; von Vaupel-Klein, Alex; den Heijer, Martin; Peters, Edgar J G; van der Valk, Marc; Reiss, Peter; Prins, Maria; Hoornenborg, Elske.
Afiliación
  • Jongen VW; Department of Infectious Diseases, Public Health Service Amsterdam, Amsterdam, The Netherlands.
  • Daans C; Stichting hiv monitoring, Amsterdam, The Netherlands.
  • van Sighem A; Department of Infectious Diseases, Public Health Service Amsterdam, Amsterdam, The Netherlands.
  • Schim van der Loeff M; Stichting hiv monitoring, Amsterdam, The Netherlands.
  • Hage K; Department of Infectious Diseases, Public Health Service Amsterdam, Amsterdam, The Netherlands.
  • Welling C; Amsterdam UMC, University of Amsterdam, Internal Medicine, Amsterdam, The Netherlands.
  • von Vaupel-Klein A; Amsterdam Institute for Infection and Immunity (AII), Amsterdam, The Netherlands.
  • den Heijer M; Amsterdam Public Health Research Institute (APH), Amsterdam, The Netherlands.
  • Peters EJG; Department of Infectious Diseases, Public Health Service Amsterdam, Amsterdam, The Netherlands.
  • van der Valk M; Amsterdam Institute for Infection and Immunity (AII), Amsterdam, The Netherlands.
  • Reiss P; Department of Infectious Diseases, Public Health Service Amsterdam, Amsterdam, The Netherlands.
  • Prins M; Department of Infectious Diseases, Public Health Service Amsterdam, Amsterdam, The Netherlands.
  • Hoornenborg E; Trans United Europe, Amsterdam, The Netherlands.
J Int AIDS Soc ; 27(8): e26317, 2024 Aug.
Article en En | MEDLINE | ID: mdl-39118295
ABSTRACT

INTRODUCTION:

Transgender women are at increased risk of acquiring HIV. Earlier studies reported lower retention in HIV care, antiretroviral therapy uptake, adherence and viral suppression. We assessed the stages of the HIV care continuum of transgender women in the Netherlands over an 11-year period. In addition, we assessed new HIV diagnoses and late presentation, as well as disengagement from care, between 2011 and 2021.

METHODS:

Using data from the Dutch national ATHENA cohort, we separately assessed viral suppression, as well as time to achieving viral suppression, among transgender women for each year between 2011 and 2021. We also assessed trends in new HIV diagnoses and late presentation (CD4 count of <350 cells/µl and/or AIDS at diagnosis), and disengagement from care.

RESULTS:

Between 2011 and 2021, a total of 260 transgender women attended at least one HIV clinical visit. Across all years, <90% of transgender women were virally suppressed (207/239 [87%] in 2021). The number of new HIV diagnoses fluctuated for transgender women (ptrend = 0.053) and late presentation was common (ranging between 10% and 67% of new HIV diagnoses). Of the 260 transgender women, 26 (10%) disengaged from care between 2011 and 2021 (incidence rate = 1.10 per 100 person-years, 95% confidence interval = 0.75-1.61).

CONCLUSIONS:

Between 2011 and 2021, less than 90% of transgender women linked to HIV care were virally suppressed. Late presentation at the time of diagnosis and disengagement from care were common. Efforts are needed to identify barriers to early HIV diagnosis and to optimize the different steps across the care continuum for transgender women.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Continuidad de la Atención al Paciente / Personas Transgénero Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: J Int AIDS Soc Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Año: 2024 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Suiza
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Continuidad de la Atención al Paciente / Personas Transgénero Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: J Int AIDS Soc Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Año: 2024 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Suiza