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Impact of luteoma during pregnancy on fetal development and its long-term effects into adulthood.
Mavrantoni, Ioanna; Borneman, Rebecca; Hittelman, Adam B; Vash-Margita, Alla.
Afiliación
  • Mavrantoni I; Gastroenterology, University Hospitals Sussex NHS Foundation Trust, Brighton, UK.
  • Borneman R; Obstetrics and Gynaecology, Yale New Haven Hospital, New Haven, Connecticut, USA.
  • Hittelman AB; Yale New Haven Hospital, New Haven, Connecticut, USA.
  • Vash-Margita A; Section of Pediatrics and Adolescent Gynecology; Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut, USA alla.vash-margita@yale.edu.
BMJ Case Rep ; 17(8)2024 Aug 07.
Article en En | MEDLINE | ID: mdl-39117365
ABSTRACT
A woman in her 30s presents to the Differences in Sexual Development Programme at a tertiary care academic medical centre with vaginal stenosis and scarring. Her medical history is significant for virilisation in utero due to a maternal luteoma of pregnancy. Laboratory investigations at the time of birth showed elevated androgens in both mother and daughter. During infancy, she underwent clitoroplasty and vaginoplasty for correction of posterior vaginal fusion. She represented as an adult with vaginal stenosis, with associated physical and psychosocial implications. She was not able to insert a tampon or have penetrative intercourse. After examination and shared decision-making, the patient underwent cystoscopy, vaginoscopy and posterior vaginoplasty with the goal to create a normal calibre vagina. Postoperative dilator use was recommended to prevent restenosis of the introitus. In clinic follow-up, the patient was observed to have a normal calibre vagina.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Neoplásicas del Embarazo / Luteoma Límite: Adult / Female / Humans / Pregnancy Idioma: En Revista: BMJ Case Rep Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Neoplásicas del Embarazo / Luteoma Límite: Adult / Female / Humans / Pregnancy Idioma: En Revista: BMJ Case Rep Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido