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Characterizing timeliness of recommended vaccinations among privately-insured children in the United States, 2009-2019.
Butler, Anne M; Newland, Jason G; Sahrmann, John M; O'Neil, Caroline A; McGrath, Leah J.
Afiliación
  • Butler AM; Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA; Department of Surgery, Division of Public Health Sciences, Washington University School of Medicine, St. Louis, MO, USA. Electronic address: anne.butler@wustl.edu.
  • Newland JG; Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, Missouri, USA; NoviSci, Durham, North, Carolina, USA. Electronic address: jgnewland@wustl.edu.
  • Sahrmann JM; Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA. Electronic address: jsahrmann@wustl.edu.
  • O'Neil CA; Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA. Electronic address: oneilc@wustl.edu.
  • McGrath LJ; Global Medical and Scientific Affairs, Pfizer Inc., New York, NY, United States. Electronic address: leah.mcgrath@pfizer.com.
Vaccine ; 42(21): 126179, 2024 Aug 30.
Article en En | MEDLINE | ID: mdl-39116485
ABSTRACT

BACKGROUND:

The Advisory Committee on Immunization Practices (ACIP) recommends early childhood vaccinations, but knowledge is limited about the magnitude and timing of vaccine delay for each recommended dose on a population level. We sought to characterize longitudinal patient-level patterns of early childhood vaccination schedule adherence.

METHODS:

Using the Merative MarketScan Commercial Database (2009-2019), we identified commercially-insured infants who received at least one timely dose of a 2-month recommended vaccine. We categorized the number of recommended vaccines administered on the same date at 2, 4, 6, and 12-15 months of age (grace period -7, +21 days). A Sankey diagram illustrated the number of vaccines received concomitantly during each age window and depicted transitions to different states over time (e.g., no vaccine delay to vaccine delay). For each vaccine dose, we estimated the cumulative incidence of receipt.

RESULTS:

Among 1,239,364 eligible children, 28% of infants aged 4 months and 38% of infants aged 6 months did not receive timely, concomitant administration of all recommended vaccines. The number of timely vaccines received concomitantly and age at receipt varied most for doses recommended during the second year of life. Children with a previously delayed (versus timely) dose consistently experienced longer time to subsequent dose.

CONCLUSIONS:

National coverage improved over time for all recommended vaccine doses under study, most notably for measles, mumps, and rubella. However, many children do not receive vaccines on schedule. Interventions to maintain adherence to the recommended schedule are needed early in life.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esquemas de Inmunización / Vacunación Límite: Child, preschool / Female / Humans / Infant / Male País/Región como asunto: America do norte Idioma: En Revista: Vaccine Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esquemas de Inmunización / Vacunación Límite: Child, preschool / Female / Humans / Infant / Male País/Región como asunto: America do norte Idioma: En Revista: Vaccine Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos