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Epidemiology and disease characteristics of myelofibrosis: a comparative analysis between Italy and global perspectives.
Breccia, Massimo; Palandri, Francesca; Polverelli, Nicola; Caira, Morena; Berluti, Michela; Palumbo, Giuseppe A; De Stefano, Valerio.
Afiliación
  • Breccia M; Dipartimento di Medicina Traslazionale e di Precisione, Sapienza Università, Roma, Italy.
  • Palandri F; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia Seragnoli, Bologna, Italy.
  • Polverelli N; Unit of Blood Diseases and stem cell transplantation, ASST Spedali Civili di Brescia, University of Brescia, Brescia, Italy.
  • Caira M; Medical Department, AbbVie Srl, Roma, Italy.
  • Berluti M; Medical Department, AbbVie Srl, Roma, Italy.
  • Palumbo GA; Dipartimento di Scienze Mediche Chirurgiche e Tecnologie Avanzate "G. F. Ingrassia", Università di Catania, Catania, Italy.
  • De Stefano V; Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche, Università Cattolica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy.
Front Oncol ; 14: 1382872, 2024.
Article en En | MEDLINE | ID: mdl-39114304
ABSTRACT
Myelofibrosis (MF) is a clonal disorder of hematopoietic stem cells characterized by altered bone marrow function and fibrosis. The aim of this narrative review is to report on the most recent epidemiologic data and to discuss features of MF and current strategies for the management of this condition in clinical practice. MF features covered by our review will include characteristics of patients with MF; myeloproliferative and myelodepletive phenotypes; MF-associated thrombosis and bleeding; risk of infections; prefibrotic and overt PMF; secondary MF. Finally, we will discuss a few aspects of MF management in clinical practice and suggest strategies for its optimization and standardization. The focus of our paper is on Italy, but relevant data from other countries will also be reviewed.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Oncol Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Oncol Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza