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Tuscany Normothermic Regional Perfusion Mobile Teams for Controlled Donation After Circulatory Death.
Lazzeri, Chiara; Manuela, Bonizzoli; Bagatti, Sara; Antonelli, Stefano; Pane, Paolo Lo; Ghinolfi, Davide; Peris, Adriano.
Afiliación
  • Lazzeri C; Regional Center for Transplant Coordination, Florence, Italy.
  • Manuela B; Intensive Care Unit, ECMO Referral Center, AOUC, Florence, Italy.
  • Bagatti S; AOUC, Florence, Italy.
  • Antonelli S; Local Transplant Authority, Gabriele Monasterio Foundation, Del Cuore Hospital, Massa, Italy.
  • Pane PL; Local Transplant Authority AUSL 6-Area Vasta Nord-Ovest, Livorno, Italy.
  • Ghinolfi D; Division of Hepatic Surgery and Liver Transplantation, University of Pisa Hospital, Pisa, Italy.
  • Peris A; Regional Center for Transplant Coordination, Florence, Italy.
Clin Transplant ; 38(8): e15429, 2024 Aug.
Article en En | MEDLINE | ID: mdl-39113667
ABSTRACT

INTRODUCTION:

To facilitate the implementation of controlled donation after circulatory death (cDCD) programs even in hospitals not equipped with a local extracorporeal membrane oxygenation (ECMO) team, some countries have launched a local cDCD network with an ECMO mobile team for normothermic regional perfusion (NRP). In the Tuscany region, in 2021, the Regional Transplant Authority launched a cDCD program to make the cDCD pathway feasible even in peripheral hospitals with NRP mobile teams, which were "converted" existing ECMO mobile teams, composed of highly skilled and experienced personnel.

METHODS:

We describe the Tuscany cDCD program, (2021-2023), for cDCD from peripheral hospitals with NRP mobile teams.

RESULTS:

Twenty-six cDCDs (26/40, 65%) came from peripheral hospitals. Following the launch of the cDCD program, cDCDs from peripheral hospitals increased, from 33% (2021) to 75% (2022 and 2023) of the overall cDCDs. The mean age was 63 years, with older donors (>75 years) in half the cases. The median warm ischemia time was 45 min (20 min are required by the Italian law for death certification), ranging from 35 to 59 min. Among the 20 livers retrieved and 18 kidneys retrieved, 16 livers, and 11 kidneys (single kidney transplantation) were transplanted, after ex vivo reperfusion, respectively.

CONCLUSIONS:

The use of NRP mobile teams proved to be feasible and safe in the management of cDCD in peripheral hospitals. No complications were reported with NRP despite the advanced age of most cDCDs.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preservación de Órganos / Perfusión / Donantes de Tejidos / Obtención de Tejidos y Órganos Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Clin Transplant Asunto de la revista: TRANSPLANTE Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Dinamarca
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preservación de Órganos / Perfusión / Donantes de Tejidos / Obtención de Tejidos y Órganos Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Clin Transplant Asunto de la revista: TRANSPLANTE Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Dinamarca