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Revisiting unstable disability and the fluctuations of frailty: a measurement burst approach.
Stolz, Erwin; Schultz, Anna; Mayerl, Hannes; Roller-Wirnsberger, Regina; Andrew, Clegg.
Afiliación
  • Stolz E; Institute of Social Medicine and Epidemiology, Medical University of Graz, Graz, Austria.
  • Schultz A; Institute of Social Medicine and Epidemiology, Medical University of Graz, Graz, Austria.
  • Mayerl H; Institute of Social Medicine and Epidemiology, Medical University of Graz, Graz, Austria.
  • Roller-Wirnsberger R; Department of Internal Medicine, Medical University of Graz, Graz, Austria.
  • Andrew C; Academic Unit for Ageing and Stroke Research, Bradford Institute for Health Research, University of Leeds, Leeds LS2 9JT, UK.
Age Ageing ; 53(8)2024 Aug 06.
Article en En | MEDLINE | ID: mdl-39113468
ABSTRACT

BACKGROUND:

It has been hypothesised that frailty is the root cause of clinically observed but rarely systematically measured unstable disability among older adults. In this study, we measure the extent of short-term disability fluctuations and estimate their association with frailty using intensive longitudinal data.

METHODS:

Repeated measurements of disability were collected under a measurement burst design in the FRequent health Assessment In Later life (FRAIL70+) study. A total of 426 community-dwelling older adults (70+) in Austria were interviewed about difficulties with basic, instrumental and mobility-related activities of daily living biweekly up to a total of 14 times in two measurement bursts (2891 and 2192 observations). Baseline frailty was assessed with both physical frailty (FP) and the frailty index (FI). Disability fluctuations were measured with the intra-individual interquartile range (iIQR) and estimated with a two-step generalised mixed regression procedure.

RESULTS:

Fewer participants were frail at baseline according to FP (11%) than FI (32%). Frail study participants reported not only more severe disability but also had more short-term disability fluctuations (iIQR = 1.0-1.5) compared with their robust counterparts (iIQR = 0). Regression models indicated that baseline frailty was associated with 2-3 times larger short-term disability fluctuations, which were also more prevalent among women, and increased with age and disability severity.

CONCLUSION:

Compared with those who were robust, frail older adults were characterised by not only more severe but also more unstable disability. Short-term disability fluctuations are closely tied to disability severity. Future studies should assess both stressors that may cause disability fluctuations among frail older adults as well as their potential consequences to inform frailty-centred care.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Actividades Cotidianas / Evaluación Geriátrica / Anciano Frágil / Evaluación de la Discapacidad / Fragilidad Límite: Aged / Aged80 / Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Age Ageing Año: 2024 Tipo del documento: Article País de afiliación: Austria Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Actividades Cotidianas / Evaluación Geriátrica / Anciano Frágil / Evaluación de la Discapacidad / Fragilidad Límite: Aged / Aged80 / Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Age Ageing Año: 2024 Tipo del documento: Article País de afiliación: Austria Pais de publicación: Reino Unido