Patient-Specific Prediction of Immediate Phase Lung Microwave Ablation Zone Size.
J Vasc Interv Radiol
; 35(11): 1635-1643, 2024 Nov.
Article
en En
| MEDLINE
| ID: mdl-39111618
ABSTRACT
PURPOSE:
To investigate the effect of patient and tumor-specific characteristics on the size of immediate phase lung microwave ablation (MWA) zone and establish a prediction model. MATERIALS ANDMETHODS:
This institutional review board (IRB)-approved, Health Insurance Portability and Accountability Act (HIPAA)-compliant cohort included 164 lesions from 99 patients who underwent computed tomography (CT)-guided lung MWA, and the 2-dimensional elliptical ground-glass opacity ablation zone was measured. Duration, maximum temperature, tumor depth, presence of emphysema, history of ipsilateral lung ablation, surgery, and radiotherapy were recorded. K-fold cross validation with k = 5 and Least Absolute Shrinkage and Selection Operator were used to build prediction models for the major and minor axes and area of the ablation zone.RESULTS:
The median of immediate phase ablation duration was 2 minutes (interquartile range, 1.5-4.25 minutes) with 65 W of power for all ablations. The mean major and minor axes and area of ablation zone were 3.1 cm (SD ± 0.6), 2.0 cm (SD ± 0.5), and 5.1 cm2 (SD ± 2.1), respectively. The major and minor axes and area of immediate phase ablation zone dimensions were significantly associated with duration (P < .001, P < .001, and P < .001, respectively), maximum temperature (P < .001, P < .001, and P < .001, respectively), tumor depth (P = .387, P < .001, and P < .001, respectively), history of ipsilateral lung ablation (P = .008, P = .286, and P = .076, respectively), and lung radiotherapy (P = .001, P = .042, and P = .015, respectively). The prediction model showed R2 values for major and minor axes and area of the ablation zone to be 0.50, 0.45, and 0.53, respectively.CONCLUSIONS:
Duration of ablation, maximum temperature, tumor depth, history of ipsilateral lung ablation, surgery, and radiotherapy were significantly associated with the ablation zone dimensions and size and can be used to build the prediction model to approximate the immediate phase lung MWA zone.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Valor Predictivo de las Pruebas
/
Técnicas de Ablación
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Neoplasias Pulmonares
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Microondas
Límite:
Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
J Vasc Interv Radiol
Asunto de la revista:
ANGIOLOGIA
/
RADIOLOGIA
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Estados Unidos