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Study protocol: perinatal mood treatment study.
Wolitzky-Taylor, Kate; Richards, Misty C; Welborn, Amelia; McDonald, Vanessa; Arnaudova, Inna; Fears, Scott; O'Mahen, Heather; Newby, Jill M; Millard, Mike; Metts, Allison V; Stein, Alan; Freimer, Nelson; Craske, Michelle G.
Afiliación
  • Wolitzky-Taylor K; University of CA - Los Angeles, 405 Hilgard Ave., Los Angeles, CA, 90025, USA. kbtaylor@mednet.ucla.edu.
  • Richards MC; University of CA - Los Angeles, 405 Hilgard Ave., Los Angeles, CA, 90025, USA.
  • Welborn A; University of CA - Los Angeles, 405 Hilgard Ave., Los Angeles, CA, 90025, USA.
  • McDonald V; University of CA - Los Angeles, 405 Hilgard Ave., Los Angeles, CA, 90025, USA.
  • Arnaudova I; University of CA - Los Angeles, 405 Hilgard Ave., Los Angeles, CA, 90025, USA.
  • Fears S; University of CA - Los Angeles, 405 Hilgard Ave., Los Angeles, CA, 90025, USA.
  • O'Mahen H; University of CA - Los Angeles, 405 Hilgard Ave., Los Angeles, CA, 90025, USA.
  • Newby JM; University of CA - Los Angeles, 405 Hilgard Ave., Los Angeles, CA, 90025, USA.
  • Millard M; University of CA - Los Angeles, 405 Hilgard Ave., Los Angeles, CA, 90025, USA.
  • Metts AV; University of CA - Los Angeles, 405 Hilgard Ave., Los Angeles, CA, 90025, USA.
  • Stein A; University of CA - Los Angeles, 405 Hilgard Ave., Los Angeles, CA, 90025, USA.
  • Freimer N; University of CA - Los Angeles, 405 Hilgard Ave., Los Angeles, CA, 90025, USA.
  • Craske MG; University of CA - Los Angeles, 405 Hilgard Ave., Los Angeles, CA, 90025, USA. mcraske@mednet.ucla.edu.
Trials ; 25(1): 525, 2024 Aug 06.
Article en En | MEDLINE | ID: mdl-39107820
ABSTRACT
Perinatal depression (PND) affects up to 20% of women and is associated with significant impairment and disability in affected women. In addition, perinatal depression is associated with broader public health and multigenerational consequences. Innovative approaches are needed to reduce the burden of perinatal depression through identification, tracking, and treatment of depressive symptoms during the perinatal period. This study is a randomized clinical trial comparing the relative efficacy of a multi-tiered system of care, Screening and Treatment of Anxiety and Depression (STAND) to perinatal care delivered by a reproductive psychiatrist in reducing symptoms of depression and anxiety. A sample of 167 individuals was randomized between week 28 of pregnancy and 6 months postpartum. A secondary aim compares the original online therapy intervention used in the first half of the study to a newer online therapy program used in the second half of the study for individuals assigned to the STAND treatment. The study measures, intervention groups, and analysis methods are described, as well as expected implications. The findings from this study may improve the methods for tracking symptom changes over time, monitoring treatment response, and providing personalized care for individuals with PND. As such, this study may improve the lives of patients with PND and their families and lower the related health care costs to society.Trial registration NCT 9/24/2021NCT direct link https//www.clinicaltrials.gov/study/NCT05056454?term=NCT05056454&rank=1&a=1 .
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ansiedad / Ensayos Clínicos Controlados Aleatorios como Asunto / Atención Perinatal / Depresión Límite: Adult / Female / Humans / Pregnancy Idioma: En Revista: Trials Asunto de la revista: MEDICINA / TERAPEUTICA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ansiedad / Ensayos Clínicos Controlados Aleatorios como Asunto / Atención Perinatal / Depresión Límite: Adult / Female / Humans / Pregnancy Idioma: En Revista: Trials Asunto de la revista: MEDICINA / TERAPEUTICA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido