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Immunisation of koalas against Chlamydia pecorum results in significant protection against chlamydial disease and mortality.
Phillips, Samuel; Hanger, Jon; Grosmaire, Julien; Mehdi, Ahmed; Jelocnik, Martina; Wong, Jessie; Timms, Peter.
Afiliación
  • Phillips S; Centre for Bioinnovation, University of the Sunshine Coast, Sippy Downs, Queensland, Australia. sphilli2@usc.edu.au.
  • Hanger J; Endeavour Veterinary Ecology, Toorbul, Queensland, Australia.
  • Grosmaire J; Endeavour Veterinary Ecology, Toorbul, Queensland, Australia.
  • Mehdi A; Queensland Cyber Infrastructure Foundation (QCIF), Facility for Advanced Bioinformatics, St Lucia, Australia.
  • Jelocnik M; Centre for Bioinnovation, University of the Sunshine Coast, Sippy Downs, Queensland, Australia.
  • Wong J; School of Science, Technology and Engineering, University of the Sunshine Coast, Sippy Downs, Queensland, Australia.
  • Timms P; Centre for Bioinnovation, University of the Sunshine Coast, Sippy Downs, Queensland, Australia.
NPJ Vaccines ; 9(1): 139, 2024 Aug 06.
Article en En | MEDLINE | ID: mdl-39107329
ABSTRACT
In 2022, the Australian Government listed the koala as endangered in several states due to habitat destruction, traffic strikes, dog attacks, and Chlamydia pecorum disease. This study evaluates a 10-year assessment of a Major Outer Membrane Protein-based vaccine's effectiveness against chlamydial disease in wild koalas from Southeast Queensland. Over a decade, 680 koalas were tracked, with five vaccine trials involving 165 koalas. While prior studies only offered up to two years of data, this study's extended period allowed a thorough evaluation of vaccine efficacy. Results showed that vaccinated koalas had significantly lower disease incidence, with a 64% reduction in chlamydial mortality. This vaccine demonstrated positive impacts on both male and female koalas, highlighting its crucial role in conserving the Australian koala population and mitigating the threats they face.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: NPJ Vaccines Año: 2024 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: NPJ Vaccines Año: 2024 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido