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Addition of pyloroplasty may improve glycemic control and refractory early satiety in gastroparesis at rates similar to gastric neurostimulation alone: a retrospective analysis.
Bauzon, Justin; Wang, Michael Y; Barber, Annabel E.
Afiliación
  • Bauzon J; Kirk Kerkorian School of Medicine, University of NV Las Vegas (UNLV), Las Vegas, NV, USA.
  • Wang MY; General Surgery, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
  • Barber AE; University of AL at Birmingham Heersink School of Medicine, Birmingham, AL, USA.
Scand J Gastroenterol ; 59(9): 1035-1038, 2024 Sep.
Article en En | MEDLINE | ID: mdl-39105565
ABSTRACT

OBJECTIVES:

Gastroparesis that is refractory to standard dietary and medical management may benefit from surgical treatment with gastric electrical neurostimulation, which has shown promise in reducing symptoms of the disease. Pyloroplasty may serve an adjunctive role to a gastric stimulator, but the precise benefit remains unclear. The present study compares reported rates of symptom improvement following gastric neurostimulator implantation with and without pyloroplasty. MATERIALS AND

METHODS:

A single center retrospective analysis of consecutive patients who received operative management for symptom refractory gastroparesis from 1 January 2020 to 31 December 2021 was performed. Subjects were assigned to cohorts based on treatment with gastric electrical stimulation alone (GES-only) or combined with pyloroplasty (GES + PP). A survey-based assessment was administered post-operatively that evaluated cardinal symptoms of gastroparesis (nausea, vomiting, early satiety) before and after treatment.

RESULTS:

In total, 42 patients (15 GES-only, 27 GES + PP) were included in the study. Both groups reported a high degree of improvement in global symptom control following surgery (93% vs 81%) with no differences between treatment cohorts (p = 0.09). Early satiety demonstrated better improvement in patients who received gastric stimulation alone (p = 0.012). Subgroup analysis of diabetic gastroparesis patients showed a 2.2% decrease in hemoglobin A1c levels in the GES + PP group (p-0.034).

CONCLUSIONS:

Symptom reduction in refractory gastroparesis appears to improve after placement of a gastric neurostimulator with or without the addition of a pyloroplasty procedure.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia por Estimulación Eléctrica / Gastroparesia Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Scand J Gastroenterol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia por Estimulación Eléctrica / Gastroparesia Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Scand J Gastroenterol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido