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Neural and Inflammatory Interactions in Wound Healing.
Zeng, Junhao; Pan, Yuyan; Chaker, Sara C; Torres-Guzman, Ricardo; Lineaweaver, William C; Qi, Fazhi.
Afiliación
  • Zeng J; From the Department of Plastic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
  • Pan Y; From the Department of Plastic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
  • Chaker SC; Department of Plastic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Torres-Guzman R; Department of Plastic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Lineaweaver WC; Department of Plastic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Qi F; From the Department of Plastic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Ann Plast Surg ; 93(2S Suppl 1): S91-S97, 2024 Aug 01.
Article en En | MEDLINE | ID: mdl-39101856
ABSTRACT
ABSTRACT The skin is an intricate network of both neurons and immunocytes, where emerging evidence has indicated that the regulation of neural-inflammatory processes may play a crucial role in mediating wound healing. Disease associated abnormal immunological dysfunction and peripheral neuropathy are implicated in the pathogenesis of wound healing impairment. However, the mechanisms through which neural-inflammatory interactions modulate wound healing remain ambiguous. Understanding the underlying mechanisms may provide novel insights to develop therapeutic devices, which could manipulate neural-inflammatory crosstalk to aid wound healing. This review aims to comprehensively illustrate the neural-inflammatory interactions during different stages of the repair process. Numerous mediators including neuropeptides secreted by the sensory and autonomic nerve fibers and cytokines produced by immunocytes play an essential part during the distinct phases of wound healing.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cicatrización de Heridas Límite: Humans Idioma: En Revista: Ann Plast Surg Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cicatrización de Heridas Límite: Humans Idioma: En Revista: Ann Plast Surg Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos