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Alternatives for the Detection and Diagnosis of Osteoarticular Infections: An Exploratory Review.
Zavaleta-Monestel, Esteban; Alpizar-Rojas, Mariela; García-Montero, Jonathan; León-Obando, Alexa; Arguedas-Chacón, Sebastián; Quesada-Villaseñor, Ricardo.
Afiliación
  • Zavaleta-Monestel E; Pharmacy, Hospital Clínica Bíblica, San José, CRI.
  • Alpizar-Rojas M; Pharmacy, Universidad de Iberoámerica, San José, CRI.
  • García-Montero J; Pharmacy and Nuclear Medicine, Hospital Clínica Bíblica, San José, CRI.
  • León-Obando A; Pharmacy and Clinical Research, Hospital Clínica Bíblica, San José, CRI.
  • Arguedas-Chacón S; Pharmacy, Universidad de Iberoámerica, San José, CRI.
  • Quesada-Villaseñor R; Pharmacy and Clinical Research, Hospital Clínica Bíblica, San José, CRI.
Cureus ; 16(7): e63743, 2024 Jul.
Article en En | MEDLINE | ID: mdl-39099945
ABSTRACT
The precise diagnosis of osteomyelitis, a bone infection, remains a significant challenge for healthcare professionals. This difficulty stems from the highly variable nature of its clinical presentation and disease course. Patients can exhibit a wide range of symptoms, making it easy to misdiagnose the condition. In turn, inaccurate diagnoses lead to inappropriate treatment regimens, potentially hindering a patient's recovery and causing unnecessary complications. Nuclear medicine offers a ray of hope in this fight against diagnostic ambiguity. It provides valuable tools, such as radiopharmaceutical imaging, that can significantly improve the accuracy of osteomyelitis diagnosis. However, limitations exist. This article explores the need for alternative diagnostic approaches within the specific context of Costa Rica. This exploration is particularly relevant due to the current regional shortage of gallium-67 (67Ga), a radiopharmaceutical commonly used in osteomyelitis diagnosis. The article delves into the nature, function, and limitations of various nuclear medicine techniques, encompassing both independent radiopharmaceuticals like 67Ga and those conjugated with specific targeting molecules to pinpoint areas of infection within the body. Given the scarcity of 67Ga in Costa Rica, it becomes crucial to explore and implement viable alternative diagnostic techniques within the healthcare system. This article emphasizes the need for further investigation into these alternatives, with the goal of improving diagnostic accuracy and ensuring optimal patient care. By implementing these alternatives, healthcare professionals in Costa Rica can effectively combat the challenges posed by osteomyelitis and pave the way for better patient outcomes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos