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Feasibility of a Novel Augmented 6-Minute Incremental Step Test: A Simplified Cardiorespiratory Fitness Assessment Tool.
Molinger, Jeroen; Kittipibul, Veraprapas; Gray, J Matthew; Rao, Vishal N; Barth, Stratton; Swavely, Ashley; Coyne, Brian; Coburn, Aubrie; Bakker, Jan; Wischmeyer, Paul E; Green, Cynthia L; MacLeod, David; Patel, Manesh; Fudim, Marat.
Afiliación
  • Molinger J; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
  • Kittipibul V; Human Pharmacology & Physiology Lab, Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA.
  • Gray JM; Division of Critical Care, Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, USA.
  • Rao VN; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
  • Barth S; Duke Clinical Research Institute, Durham, North Carolina, USA.
  • Swavely A; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
  • Coyne B; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
  • Coburn A; Duke Clinical Research Institute, Durham, North Carolina, USA.
  • Bakker J; Human Pharmacology & Physiology Lab, Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA.
  • Wischmeyer PE; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
  • Green CL; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
  • MacLeod D; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
  • Patel M; Department of Intensive Care Adults, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
  • Fudim M; Department of Medicine, NYU Grossman School of Medicine, New York, New York, USA.
JACC Adv ; 3(8): 101079, 2024 Aug.
Article en En | MEDLINE | ID: mdl-39099774
ABSTRACT

Background:

The cardiopulmonary exercise test (CPET) is considered a gold standard in assessing cardiorespiratory fitness (CRF) but has limited accessibility due to competency requirements and cost. Incorporating portable sensor devices into a simple bedside test of CRF could improve diagnostic and prognostic value.

Objectives:

The authors sought to evaluate the association of an augmented 6-minute incremental step test (6MIST) with standard CPET.

Methods:

We enrolled patients undergoing clinically indicated supine cycle ergometry CPET with invasive hemodynamics (iCPET) for the same-day 6MIST. CRF-related variables were simultaneously recorded using a signal morphology-based impedance cardiograph (PhysioFlow Enduro) and a portable metabolic analyzer (VO2 Master Pro) during incremental pace stationary stepping. The correlation between CPET and hemodynamic parameters from both tests was assessed using the intraclass correlation coefficient (ICC).

Results:

Fifteen patients (mean age 60 ± 14 years, 40% female, 27% Black) were included. All patients who agreed to undergo 6MIST completed the study without any test-related adverse events. We observed good to excellent correlation between iCPET- and 6MIST-measured CPET parameters peak heart rate (ICC = 0.60; 95% CI 0.15-0.85), absolute peak O2 consumption (VO2) (ICC = 0.77; 95% CI 0.44-0.92), relative peak VO2 (ICC = 0.64; 95% CI 0.20-0.86), maximum ventilation (ICC = 0.59; 95% CI 0.13-0.84), O2 pulse (ICC = 0.71; 95% CI 0.33-0.89), and cardiorespiratory optimal point (ICC = 0.82; 95% CI 0.52-0.94). No significant correlation was determined between iCPET and 6MIST in measuring cardiac index at rest (ICC = 0.19; 95% CI -0.34 to 0.63) or at peak exercise (ICC = 0.36; 95% CI -0.17 to 0.73).

Conclusions:

We demonstrate the feasibility of a novel augmented 6MIST with wearable devices for simultaneous CPET and hemodynamic assessment. 6MIST-measured CPET parameters were strongly correlated with the iCPET-derived measurements. Additional studies are needed to confirm the validity of the 6MIST compared to standard upright CPET.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: JACC Adv Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: JACC Adv Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos