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Adherence to antiretroviral therapy among people living with HIV attending medication-assisted treatment clinics in Dar es Salaam, Tanzania: a cross-sectional study.
Mshangila, Johnson Dominic; Mwanga, Hussein Hassan; Shao, Magdalena Edes; Msesa, Daniel Joshua; Mankaba, Christopher Nyamtuma.
Afiliación
  • Mshangila JD; Department of Official Development Assistance, Korea Foundation for International Healthcare, Dar es Salaam, Tanzania.
  • Mwanga HH; Department of Environmental and Occupational Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
  • Shao ME; Department of Environmental and Occupational Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
  • Msesa DJ; Department of Health Research, Zanzibar Health Research Institute, Zanzibar, Tanzania.
  • Mankaba CN; Division of Health, Social Welfare, and Nutrition Services, Tarime Town Council, Mara, Tanzania.
Pan Afr Med J ; 47: 186, 2024.
Article en En | MEDLINE | ID: mdl-39092019
ABSTRACT

Introduction:

the prevalence of human immunodeficiency virus (HIV) among people who inject drugs (PWIDs) in Tanzania is estimated at 35%, significantly surpassing the 4.6% HIV prevalence of the general population. People who inject drugs living with HIV have been reported to exhibit lower adherence to antiretroviral therapy (ART), leading to increased rates of mortality, morbidity, and HIV transmission. This study assessed adherence to ART and associated factors among PWIDs in Dar es Salaam.

Methods:

this cross-sectional study involved 277 PWIDs living with HIV who attended MAT clinics in Dar es Salaam from May to July 2022. Antiretroviral therapy adherence was assessed using a validated one-month self-recall medication adherence scale, and associated factors were obtained through a structured questionnaire. Statistical analyses included chi-square tests, Fisher exact tests, and log-binomial regression. Data were analyzed using STATA version 15, with a p-value of <0.05 considered statistically significant.

Results:

this study found that 83% of the study participants had a high level of adherence to ART. Additionally, the results revealed that PWIDS who consume alcohol were less likely to have high adherence to ART (aPR 0.820). On the other hand, higher odds of ART adherence were observed among participants who had family support (aPR 1.028) and those who had adequate knowledge of ART benefits (aPR 1.285).

Conclusion:

the government and development partners should implement novel interventions such as alcohol reduction programs, ART education, and expanded HIV community outreach services. These interventions have the potential to improve ART adherence and reduce HIV transmission among PWIDs.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Abuso de Sustancias por Vía Intravenosa / Fármacos Anti-VIH / Cumplimiento de la Medicación Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: Pan Afr Med J Año: 2024 Tipo del documento: Article País de afiliación: Tanzania Pais de publicación: Uganda
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Abuso de Sustancias por Vía Intravenosa / Fármacos Anti-VIH / Cumplimiento de la Medicación Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: Pan Afr Med J Año: 2024 Tipo del documento: Article País de afiliación: Tanzania Pais de publicación: Uganda