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PSA screening for prostate cancer in the United States: 30 years of controversy.
Georgiou, Loukas A; Scarbrough, Brent E.
Afiliación
  • Georgiou LA; Kentucky College of Osteopathic Medicine, University of Pikeville, 147 Sycamore St., Pikeville, KY, 41501, USA. loukasgeorgiou@upike.edu.
  • Scarbrough BE; Ross University School of Medicine, 10315 USA Today Way, Miramar, FL, 33025, USA.
J Public Health Policy ; 45(3): 552-561, 2024 Sep.
Article en En | MEDLINE | ID: mdl-39090221
ABSTRACT
In 1994, the United States approved the Prostate-Specific Antigen (PSA) test as a screening tool for prostate cancer. It did so despite the test's inherent weakness not being prostate cancer specific. Subsequent randomized trials yielded conflicting results as to its benefits. Medical guideline organizations are concerned that PSA screening results in the diagnosis and treatment of clinically indolent prostate cancer. Nevertheless, PSA screening is prevalent in North America and Europe with PSA screening increasing in other regions. We provide a critical review of the major factors that led to the prevalence of PSA screening in the United States despite the debate about its benefits. Public advocacy in favor of the test and failure of the medical community to appreciate its inherent weakness led to widespread adoption. These factors persist today. Other countries need to carefully analyze the utility of the PSA test before adopting it.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Antígeno Prostático Específico / Detección Precoz del Cáncer Límite: Humans / Male País/Región como asunto: America do norte Idioma: En Revista: J Public Health Policy Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Antígeno Prostático Específico / Detección Precoz del Cáncer Límite: Humans / Male País/Región como asunto: America do norte Idioma: En Revista: J Public Health Policy Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido