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Impact of disabilities in activities of daily living on opioid use for chronic pain in older adults: an exploratory secondary analysis from ELSI-Brazil.
Silva Godínez, J C; Minisha, F; Russo Hortencio, T D; Innocenzi, A; Dos Santos Kasai, C C; Povoa-Correa, M; Fregni, F; Pacheco-Barrios, K.
Afiliación
  • Silva Godínez JC; Harvard T. H. Chan School of Public Health, ECPE Department-PPCR Program Boston, MA, USA; Hospital de Oncología, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
  • Minisha F; Harvard T. H. Chan School of Public Health, ECPE Department-PPCR Program Boston, MA, USA; Women's Wellness and Research Centre, Hamad Medical Corporation, Doha, Qatar.
  • Russo Hortencio TD; Harvard T. H. Chan School of Public Health, ECPE Department-PPCR Program Boston, MA, USA; Faculdade São Leopoldo Mandic, Instituto de Pesquisa São Leopoldo Mandic, Campinas, Brazil.
  • Innocenzi A; Harvard T. H. Chan School of Public Health, ECPE Department-PPCR Program Boston, MA, USA; Federal University of Rio de Janeiro, Macaé, RJ, Brazil; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, RJ, Brazil.
  • Dos Santos Kasai CC; Harvard T. H. Chan School of Public Health, ECPE Department-PPCR Program Boston, MA, USA; Pontifícia Universidade Católica do Paraná- Campus Londrina, Londrina, Brazil.
  • Povoa-Correa M; Harvard T. H. Chan School of Public Health, ECPE Department-PPCR Program Boston, MA, USA; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, RJ, Brazil; Federal Institute of Cardiology (INC), Rio de Janeiro, RJ, Brazil.
  • Fregni F; Harvard T. H. Chan School of Public Health, ECPE Department-PPCR Program Boston, MA, USA; Neuromodulation Center and Center for Clinical Research Learning, Spaulding Rehabilitation Hospital and Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: felipe.fregni
  • Pacheco-Barrios K; Harvard T. H. Chan School of Public Health, ECPE Department-PPCR Program Boston, MA, USA; Neuromodulation Center and Center for Clinical Research Learning, Spaulding Rehabilitation Hospital and Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Universidad San Ignacio de Loyola
Public Health ; 235: 102-110, 2024 Oct.
Article en En | MEDLINE | ID: mdl-39089092
ABSTRACT

OBJECTIVES:

Problematic use of opioids by older adults is associated with adverse effects and has become a public health crisis worldwide. Ageing-related disabilities in activities of daily living (ADL) could promote unnecessary use of opioids in this population. This study evaluates the association between ADL disability and opioid consumption in Brazilian older adults. STUDY

DESIGN:

Study design- cross-sectional secondary data analysis of the second wave of the Brazil Longitudinal Study of Ageing (ELSI-Brazil).

METHODS:

Data from the second wave of the Brazil Longitudinal Study of Ageing (ELSI-Brazil) were used. Older adults with chronic pain were included. ADL disability was measured using the Katz Index. The primary outcome was opioid consumption for chronic pain. The primary association was explored using logistic regression models adjusting for predetermined confounders. Sensitivity analyses evaluating model performance were done by calibrating and validating the model using randomly split equal sets.

RESULTS:

In those who reported presence of chronic pain (n = 2865), the prevalence of opioid use was 29% (95% CI23.1%-35.6%). In adjusted models, participants with moderate and severe ADL disability had 1.6 (95% CI1.13-2.32; P = 0.009) and 3.8 (95% CI 1.80-7.90; P < 0.001) times higher odds of opioid consumption compared to no disability, respectively. Being female, alcohol consumption, higher pain intensity, history of dementia, fractures, and presence of ≥2 comorbidities were significantly associated with increased opioid use (P < 0.05).

CONCLUSION:

Nearly one-third of the Brazilian elderly population experiencing chronic pain reported using opioids. The functional decline during the process of ageing appears to be a risk factor for pain intolerance and opioid use. Multidisciplinary approaches to detect early ADL disabilities and improve mobility and access to assistive technologies need to be established to prevent opioid overuse and addiction in elderly populations.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Actividades Cotidianas / Personas con Discapacidad / Dolor Crónico / Analgésicos Opioides Límite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: America do sul / Brasil Idioma: En Revista: Public Health Año: 2024 Tipo del documento: Article País de afiliación: México Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Actividades Cotidianas / Personas con Discapacidad / Dolor Crónico / Analgésicos Opioides Límite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: America do sul / Brasil Idioma: En Revista: Public Health Año: 2024 Tipo del documento: Article País de afiliación: México Pais de publicación: Países Bajos