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A Case Report on Trastuzumab Emtansine (T-DM1) in a Patient With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Breast Cancer and Brain Metastases: Long-Term Treatment and Survival.
Doshi, Vipul; Thummar, Vipulkumar; Mehta, Priya.
Afiliación
  • Doshi V; Medical Oncology, Solapur Cancer Centre, Solapur, IND.
  • Thummar V; Medical Affairs, Zydus Lifesciences Ltd, Ahmedabad, IND.
  • Mehta P; Medical Affairs, Zydus Lifesciences Ltd, Ahmedabad, IND.
Cureus ; 16(7): e63589, 2024 Jul.
Article en En | MEDLINE | ID: mdl-39087186
ABSTRACT
Breast cancer remains the most common cancer in women worldwide. Among women with breast cancer, brain metastases are very prevalent among HER2-positive and affect those in the advanced stages of the disease. Various factors, including molecular subtypes, performance status, extracranial disease status, leptomeningeal metastasis, and the number of lesions, significantly influence the prognosis of patients with brain metastases from breast cancer (BCBrM). Understanding and addressing the specific risks associated with different breast cancer subtypes is crucial for developing tailored and effective medical treatments. This report presents a case of a breast cancer patient with recurrent disease and brain metastases who achieved long-term survival following a treatment regimen that included radiotherapy and a T-DM1 biosimilar.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos