Your browser doesn't support javascript.
loading
In-silico analysis of hemodynamic indicators in idealized stented coronary arteries for varying stent indentation.
Ranno, A M; Manjunatha, K; Glitz, A; Schaaps, N; Reese, S; Vogt, F; Behr, M.
Afiliación
  • Ranno AM; Chair for Computational Analysis of Technical Systems (CATS), RWTH Aachen University, Aachen, Germany.
  • Manjunatha K; Institute of Applied Mechanics (IFAM), RWTH Aachen University, Aachen, Germany.
  • Glitz A; Department of Cardiology, Vascular Medicine and Intensive Care (CARD), RWTH Aachen University, Aachen, Germany.
  • Schaaps N; Department of Cardiology, Vascular Medicine and Intensive Care (CARD), RWTH Aachen University, Aachen, Germany.
  • Reese S; Institute of Applied Mechanics (IFAM), RWTH Aachen University, Aachen, Germany.
  • Vogt F; Department of Cardiology, Vascular Medicine and Intensive Care (CARD), RWTH Aachen University, Aachen, Germany.
  • Behr M; Chair for Computational Analysis of Technical Systems (CATS), RWTH Aachen University, Aachen, Germany.
Comput Methods Biomech Biomed Engin ; : 1-22, 2024 Jul 31.
Article en En | MEDLINE | ID: mdl-39086224
ABSTRACT
In this work, we investigate the effects of stent indentation on hemodynamic indicators in stented coronary arteries. Our aim is to assess in-silico risk factors for in-stent restenosis (ISR) and thrombosis after stent implantation. The proposed model is applied to an idealized artery with Xience V stent for four indentation percentages and three mesh refinements. We analyze the patterns of hemodynamic indicators arising from different stent indentations and propose an analysis of time-averaged WSS (TAWSS), topological shear variation index (TSVI), oscillatory shear index (OSI), and relative residence time (RRT). We observe that higher indentations display higher frequency of critically low TAWSS, high TSVI, and non-physiological OSI and RRT. Furthermore, an appropriate mesh refinement is needed for accurate representation of hemodynamics in the stent vicinity. The results suggest that disturbed hemodynamics could play a role in the correlation between high indentation and ISR.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Comput Methods Biomech Biomed Engin Asunto de la revista: ENGENHARIA BIOMEDICA / FISIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Comput Methods Biomech Biomed Engin Asunto de la revista: ENGENHARIA BIOMEDICA / FISIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido