Advancements in Structural Biology How to See Molecules of Life? / Postepy biologii strukturalnej jak zobaczyc czasteczki zycia?
Postepy Biochem
; 70(2): 128-138, 2024 07 01.
Article
en Pl
| MEDLINE
| ID: mdl-39083468
ABSTRACT
Structural biology is focused on understanding the architecture of biomolecules, such as proteins and nucleic acids. Deciphering the structure helps to understand their function in the cell at a very precise molecular level. This makes it possible to not only determine the basis of diseases but also to propose therapeutic strategies and tools. Such a strong motivation for the development of structural biology has led to the development of a number of methods, which enable determination of the structures of the molecules of life. The continuous progress has been enabled by the integration of biology, chemistry, physics, and computer science, making structural biology extremely interdisciplinary. In its 35-year history, the Institute of Bioorganic Chemistry of the Polish Academy of Sciences in Poznan has become one of the key Polish institutions conducting research in the field of structural biology. On one hand, the research has brought international recognition, and on the other hand, it has forced the implementation and development of cutting-edge methods. This review discusses the methods used in structural biology at the Institute.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Proteínas
Límite:
Humans
País/Región como asunto:
Europa
Idioma:
Pl
Revista:
Postepy Biochem
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Polonia