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Gastric Signet Ring Cell Adenocarcinoma With Metastasis to the Testicles and Leptomeninges.
Shariff, Hamzah; Luu, Tristan; Kavis, Haluk; Obuch, Joshua.
Afiliación
  • Shariff H; Geisinger Commonwealth School of Medicine, Scranton, PA.
  • Luu T; Department of Internal Medicine, Geisinger Wyoming Valley Medical Center, Wilkes Barre, PA.
  • Kavis H; Department of Clinical and Laboratory Pathology, Geisinger Medical Center, Danville, PA.
  • Obuch J; Department of Gastroenterology, Geisinger Wyoming Valley Medical Center, Wilkes Barre, PA.
ACG Case Rep J ; 11(8): e01419, 2024 Aug.
Article en En | MEDLINE | ID: mdl-39081301
ABSTRACT
Gastric signet ring cell adenocarcinoma (SRCA) is an aggressive malignancy primarily diagnosed in advanced stages. Metastasis to other organ systems is uncommon, however, associated with poor prognosis. We present a young patient with persistent pain in the testicle. Histopathologic examination of the resected testicle revealed metastatic signet ring adenocarcinoma prompting follow-up endoscopy with biopsy confirming gastric SRCA. After 10 months of systemic chemotherapy, the patient developed worsening headaches, and cerebrospinal fluid cytology confirmed leptomeningeal metastasis. This case underscores the rare manifestation of SRCA and the importance of vigilance for atypical presentations to ensure timely diagnosis and management.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: ACG Case Rep J Año: 2024 Tipo del documento: Article País de afiliación: Panamá Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: ACG Case Rep J Año: 2024 Tipo del documento: Article País de afiliación: Panamá Pais de publicación: Estados Unidos