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Prevalence of non-communicable diseases among household contacts of people with tuberculosis: A systematic review and individual participant data meta-analysis.
Hamada, Yohhei; Quartagno, Matteo; Malik, Farihah; Ntshamane, Keolebogile; Tisler, Anna; Gaikwad, Sanjay; Acuna-Villaorduna, Carlos; Bhavani, Perumal Kannabiran; Alisjahbana, Bachti; Ronacher, Katharina; Apriani, Lika; Becerra, Mercedes; Chu, Alexander L; Creswell, Jacob; Diaz, Gustavo; Ferro, Beatriz E; Galea, Jerome T; Grandjean, Louis; Grewal, Harleen M S; Gupta, Amita; Jones-López, Edward C; Kleynhans, Léanie; Lecca, Leonid; MacPherson, Peter; Murray, Megan; Marín, Diana; Restrepo, Blanca I; Shivakumar, Shri Vijay Bala Yogendra; Shu, Eileen; Sivakumaran, Dhanasekaran; Vo, Luan Nguyen Quang; Webb, Emily L; Copas, Andrew; Abubakar, Ibrahim; Rangaka, Molebogeng X.
Afiliación
  • Hamada Y; Institute for Global Health, University College London, London, UK.
  • Quartagno M; MRC Clinical Trials Unit, Institute of Clinical Trials and Methodology, University College London, London, UK.
  • Malik F; UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Ntshamane K; The Aurum Institute, Johannesburg, South Africa.
  • Tisler A; Institute for Global Health, University College London, London, UK.
  • Gaikwad S; Institute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
  • Acuna-Villaorduna C; BJ Government Medical College and Sassoon General Hospitals, Pune, India.
  • Bhavani PK; Boston University Medical Center, Section of Infectious Diseases, Boston, Massachusetts, USA.
  • Alisjahbana B; ICMR-National Institute for Research in Tuberculosis, Chennai, India.
  • Ronacher K; Research Center for Care and Control of Infectious Diseases (RC3ID), Universitas Padjadjaran, Bandung, Indonesia.
  • Apriani L; Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran/Hasan Sadikin Hospital, Bandung, Indonesia.
  • Becerra M; DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, SA MRC Centre for TB Research, Division of Molecular Biology and Human Genetics, Department of Molecular Biology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
  • Chu AL; Mater Research Institute, Translational Research Institute, The University of Queensland, Brisbane, Australia.
  • Creswell J; Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Australia.
  • Diaz G; Research Center for Care and Control of Infectious Diseases (RC3ID), Universitas Padjadjaran, Bandung, Indonesia.
  • Ferro BE; Department of Public Health, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.
  • Galea JT; Socios En Salud, Lima, Peru.
  • Grandjean L; Department of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USA.
  • Grewal HMS; Department of Medical Education, Dell Medical School at the University of Texas at Austin, Austin, Texas, USA.
  • Gupta A; Stop TB Partnership, Innovations and Grants, Geneva, Switzerland.
  • Jones-López EC; Centro Internacional de Entrenamiento e Investigaciones Médicas-CIDEIM, Cali, Valle del Cauca, Colombia.
  • Kleynhans L; Universidad Icesi, Cali, Valle del Cauca, Colombia.
  • Lecca L; Departamento de Ciencias Básicas Médicas, Facultad de Ciencias de la Salud, Universidad Icesi, Cali, Colombia.
  • MacPherson P; Department of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USA.
  • Murray M; School of Social Work, University of South Florida, Tampa, Florida, USA.
  • Marín D; UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Restrepo BI; Department of Clinical Science, Bergen Integrated Diagnostic Stewardship Cluster, Faculty of Medicine, University of Bergen, Bergen, Norway.
  • Shivakumar SVBY; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Shu E; Division of Infectious Diseases, Department of Medicine, Keck School of Medicine of USC, University of Southern California, Los Angeles, California, USA.
  • Sivakumaran D; DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, SA MRC Centre for TB Research, Division of Molecular Biology and Human Genetics, Department of Molecular Biology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
  • Vo LNQ; Mater Research Institute, Translational Research Institute, The University of Queensland, Brisbane, Australia.
  • Webb EL; Socios En Salud, Lima, Peru.
  • Copas A; Department of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USA.
  • Abubakar I; School of Health & Wellbeing, University of Glasgow, Glasgow, UK.
  • Rangaka MX; Clinical Research Department, London School of Hygiene & Tropical Medicine, London, UK.
Trop Med Int Health ; 29(9): 768-780, 2024 Sep.
Article en En | MEDLINE | ID: mdl-39073229
ABSTRACT

OBJECTIVE:

To investigate the prevalence of non-communicable diseases among household contacts of people with tuberculosis.

METHODS:

We conducted a systematic review and individual participant data meta-analysis. We searched Medline, Embase and the Global Index Medicus from inception to 16 May 2023. We included studies that assessed for at least one non-communicable disease among household contacts of people with clinical tuberculosis. We estimated the non-communicable disease prevalence through mixed effects logistic regression for studies providing individual participant data, and compared it with estimates from aggregated data meta-analyses. Furthermore, we compared age and sex-standardised non-communicable disease prevalence with national-level estimates standardised for age and sex.

RESULTS:

We identified 39 eligible studies, of which 14 provided individual participant data (29,194 contacts). Of the remaining 25 studies, 18 studies reported aggregated data suitable for aggregated data meta-analysis. In individual participant data analysis, the pooled prevalence of diabetes in studies that undertook biochemical testing was 8.8% (95% confidence interval [CI], 5.1%-14.9%, four studies). Age-and sex-standardised prevalence was higher in two studies (10.4% vs. 6.9% and 11.5% vs. 8.4%) than the corresponding national estimates and similar in two studies. Prevalence of diabetes mellitus based on self-report or medical records was 3.4% (95% CI 2.6%-4.6%, 14 studies). Prevalence did not significantly differ compared to estimates from aggregated data meta-analysis. There were limited data for other non-communicable diseases.

CONCLUSION:

The prevalence of diabetes mellitus among household contacts was high while that of known diabetes was substantially lower, suggesting the underdiagnosis. tuberculosis household contact investigation offers opportunities to deliver multifaceted interventions to identify tuberculosis infection and disease, screen for non-communicable diseases and address shared risk factors.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis / Composición Familiar / Enfermedades no Transmisibles Límite: Humans Idioma: En Revista: Trop Med Int Health Asunto de la revista: MEDICINA TROPICAL / SAUDE PUBLICA Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis / Composición Familiar / Enfermedades no Transmisibles Límite: Humans Idioma: En Revista: Trop Med Int Health Asunto de la revista: MEDICINA TROPICAL / SAUDE PUBLICA Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido