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Substituted Maleimides: Self-Reportable Linkers and Tags in Bioconjugation, Material Science, and Nanotechnology.
Barker, Jake; Tibbetts, Joshua; Ferguson, Calum; Xie, Yujie; O'Reilly, Rachel Kerry.
Afiliación
  • Barker J; University of Birmingham, Chemistry, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.
  • Tibbetts J; University of Birmingham, Chemistry, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.
  • Ferguson C; University of Birmingham, Chemistry, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.
  • Xie Y; Shanghai University, School of Medicine, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.
  • O'Reilly RK; University of Birmingham, Dept. of Chemistry, School of Chemistry, University of Birmingham, B15 2TT, Edgbaston, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.
Angew Chem Int Ed Engl ; : e202410550, 2024 Jul 28.
Article en En | MEDLINE | ID: mdl-39073204
ABSTRACT
Substituted maleimides are customisable fluorescent linkers and probes with adaptable reactivity and optical properties. Their compact nature and tunability has led to their use in various applications. For example, their solvatochromic properties offer real-time feedback on linking chemistry and environmental changes, essential for applications in material labelling, drug delivery, and nanoparticle functionalization. This review focuses on developing, synthesising, and modifying substituted maleimides as environment-sensitive fluorescent linkers and probes. It delves into their photophysical dynamics and strategic applications, highlighting their significant contributions to macromolecule conjugation and the development of self-reporting materials.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Angew Chem Int Ed Engl Año: 2024 Tipo del documento: Article Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Angew Chem Int Ed Engl Año: 2024 Tipo del documento: Article Pais de publicación: Alemania