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Non-surgical Treatment of Severe Drug-Influenced Gingival Enlargement: A Report of Two Cases.
Fidan, Ibrahim; Delamotte, Edouard; Colombier, Marie-Laure; Agossa, Kevimy.
Afiliación
  • Fidan I; Department of Periodontology, University of Lille, School of Dentistry, Centre Hospitalier Universitaire (CHU) Lille, Lille, FRA.
  • Delamotte E; Department of Periodontology, Paris Cité University, Montrouge, FRA.
  • Colombier ML; Department of Oral Medicine, Louis Mourier Hospital, Assistance Publique - Hôpitaux de Paris (AP-HP), Colombes, FRA.
  • Agossa K; Department of Periodontology, University of Lille, School of Dentistry, Centre Hospitalier Universitaire (CHU) Lille, Lille, FRA.
Cureus ; 16(6): e63214, 2024 Jun.
Article en En | MEDLINE | ID: mdl-39070408
ABSTRACT
Drug-influenced gingival enlargement (DIGE) is a well-known adverse drug reaction associated with multiple medications. Although a benign condition, DIGE can have a significant impact on patients' aesthetic comfort and function. A surgical resection approach is usually proposed to treat severe and generalized DIGE. In this report, we describe the cases of a 47-year-old male and a 58-year-old male, both presenting with severe and generalized DIGE associated with amlodipine, a calcium channel blocker used for hypertension treatment. A non-surgical, cause-related approach, including drug substitution and repeated sessions of mechanical instrumentation, led to the complete resolution of severe DIGE, with no recurrence observed after 18 months in Case 1 and 12 months in Case 2. Throughout the observation period, the bleeding on probing score decreased from 100% at baseline to 10% or less, and the number of periodontal sites with probing pocket depth ≥ 5 mm decreased by more than 90% compared to the initial assessment. Both patients reported a high level of satisfaction with the treatment outcomes. These successful results should encourage clinicians to give greater consideration to non-surgical management of DIGE as a less invasive option before proceeding to surgical treatments.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos