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The added value of a new high-performance ring-gantry CBCT imaging system for prostate cancer patients.
Kunnen, Britt; J A J van de Schoot, Agustinus; Fremeijer, Kimm P; Nicolai-Koornneef, Elise M; Offereins-van Harten, Kirsten; Sluijter, Judith H; Sijtsema, Nienke D; Oomen-de Hoop, Esther; El Yaakoubi, Abdelmounaim; Froklage, Femke E; de Vries, Kim C; Dirkx, Maarten L P; Penninkhof, Joan J; Petit, Steven F.
Afiliación
  • Kunnen B; Department of Radiotherapy, Erasmus MC Cancer Institute, Rotterdam, the Netherlands. Electronic address: b.kunnen@erasmusmc.nl.
  • J A J van de Schoot A; Department of Radiotherapy, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • Fremeijer KP; Department of Radiotherapy, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • Nicolai-Koornneef EM; Department of Radiotherapy, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • Offereins-van Harten K; Department of Radiotherapy, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • Sluijter JH; Department of Radiotherapy, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • Sijtsema ND; Department of Radiotherapy, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • Oomen-de Hoop E; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • El Yaakoubi A; Department of Radiotherapy, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • Froklage FE; Department of Radiotherapy, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • de Vries KC; Department of Radiotherapy, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • Dirkx MLP; Department of Radiotherapy, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • Penninkhof JJ; Department of Radiotherapy, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • Petit SF; Department of Radiotherapy, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Radiother Oncol ; 200: 110458, 2024 Jul 26.
Article en En | MEDLINE | ID: mdl-39069089
ABSTRACT
BACKGROUND AND

PURPOSE:

A novel Cone-Beam Computed Tomography (CBCT) named HyperSight provides superior CBCT image quality compared to conventional ring gantry CBCT imaging, and it is suitable for dose calculations for prostate cancer, but it comes with considerable additional costs. The aim of this study was to determine the added value of HyperSight CBCT imaging compared to conventional CBCT imaging in terms of organ visibility in the male pelvic region. MATERIALS AND

METHODS:

Twenty prostate cancer patients were included in this prospective clinical study. For each patient three CBCT pairs, consisting of HyperSight and conventional CBCT scans acquired on consecutive days, were included. CBCT scans were evaluated by four observers in terms of visibility of the prostate, bladder, rectum and seminal vesicles. Visibility was scored on a 1-to-5 scale and by annotating axial slices where the organs were hard to delineate. Lastly, observers indicated whether the CBCT scans were of sufficient quality for an online adaptive radiation therapy workflow.

RESULTS:

All four organs were better visible on HyperSight CBCT scans compared to conventional CBCT scans. The mean visibility scores increased from 3.1 to 4.5 on a 1--5 scale of and the mean number of annotated slices reduced from 4.5 to 1.1. 99% Of the HyperSight CBCT scans were considered suitable for an online adaptive workflow vs 25-83% for the conventional CBCT scans.

CONCLUSION:

HyperSight CBCT scans yielded a visibility of prostate, bladder, rectum and seminal vesicles comparable to planning CT scans and, can replace a repeat planning CT scan in case of anatomical changes requiring a new treatment plan.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Radiother Oncol Año: 2024 Tipo del documento: Article Pais de publicación: Irlanda
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Radiother Oncol Año: 2024 Tipo del documento: Article Pais de publicación: Irlanda