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Addition of operative hysteroscopy to vacuum aspiration for the management of early pregnancy loss after in vitro fertilization.
Hu, Kai-Lun; Zhao, Jie; Lin, Mingmei; Wang, Xiaoye; Qi, Linjing; Liu, Huan; Mo, Dan; Zeng, Zhonghong; Mol, Ben W; Li, Rong.
Afiliación
  • Hu KL; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China; Key Laboratory of Assisted Reproduction, Peking University, Ministry of Education, Beijing, People's Republic of China; Beijing Key Laboratory of Reproduc
  • Zhao J; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China.
  • Lin M; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China.
  • Wang X; Birth Control Department, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China.
  • Qi L; Birth Control Department, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China.
  • Liu H; Linyi Central Hospital, Linyi City, Shandong Province, People's Republic of China.
  • Mo D; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China; The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People's Republic of China.
  • Zeng Z; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China; The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People's Republic of China.
  • Mol BW; Department of Obstetrics and Gynaecology, Monash University, Clayton, Melbourne, Victoria, Australia; Aberdeen Centre for Women's Health Research, University of Aberdeen, Aberdeen, United Kingdom.
  • Li R; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, People's Republic of China; Key Laboratory of Assisted Reproduction, Peking University, Ministry of Education, Beijing, People's Republic of China; Beijing Key Laboratory of Reproduc
Fertil Steril ; 2024 Jul 25.
Article en En | MEDLINE | ID: mdl-39067673
ABSTRACT

OBJECTIVE:

To investigate whether operative hysteroscopy in addition to vacuum aspiration for the management of early pregnancy loss effectively increases the success rate of subsequent frozen embryo transfer.

DESIGN:

Propensity score-matched cohort study.

SETTING:

Academic hospital. PATIENT(S) Women with a miscarriage at 5-16 gestational weeks during an in vitro fertilization cycle in Peking University Third Hospital from 2015 to 2022. INTERVENTION(S) Hysteroscopy plus vacuum aspiration vs. conventional vacuum aspiration. MAIN OUTCOME MEASURE(S) Live birth rate in the subsequent frozen embryo transfer. RESULT(S) A total of 347 women who underwent vacuum aspiration plus hysteroscopy and 2,562 women who underwent conventional vacuum aspiration were included in the analysis. After propensity score matching (11 ratio), 325 women were included in each group. Compared with women who underwent vacuum aspiration, those who underwent vacuum aspiration plus hysteroscopy were associated with a lower rate of live birth in the propensity score-based matched cohort (22% vs. 30%; adjusted odds ratio, 0.68 [0.47-0.97]). Biochemical, clinical, and multiple pregnancy rates were not significantly different, as was the miscarriage rate. In the overall cohort, 11 women experienced surgery reintervention in the vacuum aspiration group (0.4%), whereas none required surgery reintervention in the vacuum aspiration plus hysteroscopy group. CONCLUSION(S) Women who underwent vacuum aspiration plus hysteroscopy may be associated with lower rates of live birth than those who underwent vacuum aspiration. Further studies are necessary to establish this relationship definitively.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Fertil Steril Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Fertil Steril Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos