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Proline Metabolism Genes in Transgenic Plants: Meta-Analysis under Drought and Salt Stress.
Renzetti, Marco; Bertolini, Elisa; Trovato, Maurizio.
Afiliación
  • Renzetti M; Department of Biology and Biotechnologies, Sapienza University, 00185 Rome, Italy.
  • Bertolini E; Biocomputing Group, Department of Pharmacy and Biotechnology, Bologna University, 40126 Bologna, Italy.
  • Trovato M; Department of Biology and Biotechnologies, Sapienza University, 00185 Rome, Italy.
Plants (Basel) ; 13(14)2024 Jul 11.
Article en En | MEDLINE | ID: mdl-39065440
ABSTRACT
The amino acid proline accumulates in plants during abiotic stresses such as drought and salinity and is considered a reliable marker of environmental stress. While its accumulation is well established, its precise role in stress tolerance and its underlying molecular mechanism remain less clear. To address these issues, we performed a meta-analysis-a robust statistical technique that synthesizes results from multiple independent studies while accounting for experimental differences. We focused on 16 physiological and morphological parameters affected by drought and salt stress in transgenic plants expressing proline metabolic genes. For each parameter, we calculated the effect size as the response ratio (RR), which represents the logarithm of the mean value in the transgenic group over the mean value of the control group (lnRR). Under stress, most parameters exhibited significantly higher response ratios in the transgenic group, confirming the beneficial effects of proline during drought and salt stress. Surprisingly, under non-stressed conditions, most stress markers showed no significant differences between transgenic and non-transgenic plants, despite elevated proline levels in the former. These results suggest that the benefits of proline may be related to proline catabolism or may only become apparent during stress, possibly due to interactions with reactive oxygen species (ROS), which accumulate predominantly under stress conditions.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Plants (Basel) Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Plants (Basel) Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza