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Improvement of Metabolic-Associated Fatty Liver Disease by Magnetic Resonance Spectroscopy in Morbidly Obese Women Undergoing Roux-en-Y Gastric Bypass, following a Postoperative Mediterranean-like Diet.
Ruiz-Tovar, Jaime; Llavero, Carolina; Rodriguez-Ortega, Maria; De Castro, Nuria M; Martín-Crespo, Maria Cristina; Escobar-Aguilar, Gema; Martin-Nieto, Ana; Gonzalez, Gilberto.
Afiliación
  • Ruiz-Tovar J; San Juan de Dios Foundation, 28036 Madrid, Spain.
  • Llavero C; Health Sciences Department, San Juan de Dios School of Nursing and Physical Therapy, Comillas Pontifical University, 28036 Madrid, Spain.
  • Rodriguez-Ortega M; Obesity Unit, Garcilaso Clinic, 28010 Madrid, Spain.
  • De Castro NM; San Juan de Dios Foundation, 28036 Madrid, Spain.
  • Martín-Crespo MC; Health Sciences Department, San Juan de Dios School of Nursing and Physical Therapy, Comillas Pontifical University, 28036 Madrid, Spain.
  • Escobar-Aguilar G; San Juan de Dios Foundation, 28036 Madrid, Spain.
  • Martin-Nieto A; Health Sciences Department, San Juan de Dios School of Nursing and Physical Therapy, Comillas Pontifical University, 28036 Madrid, Spain.
  • Gonzalez G; San Juan de Dios Foundation, 28036 Madrid, Spain.
Nutrients ; 16(14)2024 Jul 16.
Article en En | MEDLINE | ID: mdl-39064723
ABSTRACT
(1)

Background:

Bariatric surgery has demonstrated the capacity to improve metabolic-associated fatty liver disease (MAFLD) in patients with morbid obesity. In addition, the Mediterranean diet contains anti-inflammatory, anti-oxidative, and anti-fibrotic components, promoting a beneficial effect on MAFLD. This study aimed to assess the improvement of MAFLD, specifically liver steatosis, in morbidly obese patients undergoing Roux-en-Y gastric bypass (RYGB) and following a hypocaloric Mediterranean-like diet. (2)

Methods:

A prospective observational pilot study of 20 patients undergoing RYGB was conducted. The participants underwent a magnetic resonance spectroscopy study 2 weeks before the surgical act and one year postoperatively to assess the percentage of lipid content (PLC). The adherence to the Mediterranean diet was determined by the KIDMED test 1 year after surgery. (3)

Results:

Mean baseline PLC was 14.2 ± 9.4%, and one year after surgery, it decreased to 4.0 ± 1.8% (p < 0.001). A total of 12 patients (60%) were within the range of moderate adherence to the Mediterranean diet, whereas 8 patients (40%) showed a high adherence. The patients with high adherence to the Mediterranean diet presented significantly lower values of postoperative PLC. (4)

Conclusions:

Liver steatosis significantly reduces after RYGB. This reduction is further improved when associated with a high adherence to a Mediterranean diet.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obesidad Mórbida / Espectroscopía de Resonancia Magnética / Derivación Gástrica / Dieta Mediterránea Límite: Adult / Female / Humans / Middle aged Idioma: En Revista: Nutrients Año: 2024 Tipo del documento: Article País de afiliación: España Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obesidad Mórbida / Espectroscopía de Resonancia Magnética / Derivación Gástrica / Dieta Mediterránea Límite: Adult / Female / Humans / Middle aged Idioma: En Revista: Nutrients Año: 2024 Tipo del documento: Article País de afiliación: España Pais de publicación: Suiza