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Intradevice Repeatability and Interdevice Comparison of Two Specular Microscopy Devices in a Real-Life Setting: Tomey EM-4000 and Nidek CEM-530.
Kecik, Mateusz; Kropp, Martina; Thumann, Gabriele; Pajic, Bojan; Guber, Josef; Guber, Ivo.
Afiliación
  • Kecik M; Department of Ophthalmology, University of Geneva, 1205 Geneva, Switzerland.
  • Kropp M; Experimental Ophthalmology, University of Geneva, 1205 Geneva, Switzerland.
  • Thumann G; Department of Ophthalmology, University of Geneva, 1205 Geneva, Switzerland.
  • Pajic B; Experimental Ophthalmology, University of Geneva, 1205 Geneva, Switzerland.
  • Guber J; Department of Ophthalmology, University of Geneva, 1205 Geneva, Switzerland.
  • Guber I; Experimental Ophthalmology, University of Geneva, 1205 Geneva, Switzerland.
Medicina (Kaunas) ; 60(7)2024 Jul 09.
Article en En | MEDLINE | ID: mdl-39064539
ABSTRACT
Background and

Objectives:

The purpose of this study was to compare two commercially available specular microscopes (Tomey EM-4000 and Nidek CEM-530) in a real-life clinical setting in terms of intra- and interdevice variability. The study was conducted on all patients seen in a clinical practice specializing in anterior segment pathologies, regardless of the purpose of their visit. Materials and

Methods:

In total, 112 eyes of 56 patients (age 23-85 years old) were included in the study. Each eye was measured three times with each device (for a total of six measurements), and results for central corneal thickness (CCT) and corneal endothelial cell density (ECD) were recorded. The results were then evaluated with the D'Agostino-Pearson normality test and compared with a Wilcoxon signed-rank test, t-test, ANOVA or Mann-Whitney test for intra- and interdevice variability.

Results:

Both specular microscopes produced very reliable reproducible intradevice

results:

The Tomey EM-4000 measured an ECD of 2390 ± 49.57 cells/mm2 (mean ± standard error of mean); the range was 799-3010 cells/mm2. The determined CCT was 546 ± 5.104 µm (mean ± standard error of mean [SEM]); the range was 425-615 µm. The measurements with the Nidek CEM-530 revealed an ECD of 2417 ± 0.09 cells/mm2 (mean ± SEM); the range was 505-3461 cells/mm2 (mean ± SEM). The mean CCT detected was 546.3 ± 4.937 µm (mean ± SEM); the range was 431-621 µm. The interdevice differences were statistically significant for both parameters, ECD (p = 0.0175) and CCT (p = 0.0125) (p < 0.05).

Conclusions:

The Nidek CEM-530 and the Tomey EM-4000 both produced reliable and reproducible results in terms of ECD and CCT. The absolute measurements were statistically significantly different for CCT and ECD for both devices; the Nidek produces slightly higher values.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microscopía Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Medicina (Kaunas) Asunto de la revista: MEDICINA Año: 2024 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microscopía Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Medicina (Kaunas) Asunto de la revista: MEDICINA Año: 2024 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Suiza