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Four Transformer-Based Deep Learning Classifiers Embedded with an Attention U-Net-Based Lung Segmenter and Layer-Wise Relevance Propagation-Based Heatmaps for COVID-19 X-ray Scans.
Gupta, Siddharth; Dubey, Arun K; Singh, Rajesh; Kalra, Mannudeep K; Abraham, Ajith; Kumari, Vandana; Laird, John R; Al-Maini, Mustafa; Gupta, Neha; Singh, Inder; Viskovic, Klaudija; Saba, Luca; Suri, Jasjit S.
Afiliación
  • Gupta S; Department of Computer Science and Engineering, Bharati Vidyapeeth's College of Engineering, New Delhi 110063, India.
  • Dubey AK; Department of Information Technology, Bharati Vidyapeeth's College of Engineering, New Delhi 110063, India.
  • Singh R; Department of Research and Innovation, Uttaranchal Institute of Technology, Uttaranchal University, Dehradun 248007, India.
  • Kalra MK; Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
  • Abraham A; Department of Computer Science, Bennett University, Greater Noida 201310, India.
  • Kumari V; School of Computer Science and Engineering, Galgotias University, Greater Noida 201310, India.
  • Laird JR; Heart and Vascular Institute, Adventist Health St. Helena, St. Helena, CA 94574, USA.
  • Al-Maini M; Allergy, Clinical Immunology and Rheumatology Institute, Toronto, ON M5G 1N8, Canada.
  • Gupta N; Department of Information Technology, Bharati Vidyapeeth's College of Engineering, New Delhi 110063, India.
  • Singh I; Department of Radiology and Ultrasound, University Hospital for Infectious Diseases, 10000 Zagreb, Croatia.
  • Viskovic K; Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.), 09100 Cagliari, Italy.
  • Saba L; Department of ECE, Idaho State University, Pocatello, ID 83209, USA.
  • Suri JS; Department of ECE, Idaho State University, Pocatello, ID 83209, USA.
Diagnostics (Basel) ; 14(14)2024 Jul 16.
Article en En | MEDLINE | ID: mdl-39061671
ABSTRACT

Background:

Diagnosing lung diseases accurately is crucial for proper treatment. Convolutional neural networks (CNNs) have advanced medical image processing, but challenges remain in their accurate explainability and reliability. This study combines U-Net with attention and Vision Transformers (ViTs) to enhance lung disease segmentation and classification. We hypothesize that Attention U-Net will enhance segmentation accuracy and that ViTs will improve classification performance. The explainability methodologies will shed light on model decision-making processes, aiding in clinical acceptance.

Methodology:

A comparative approach was used to evaluate deep learning models for segmenting and classifying lung illnesses using chest X-rays. The Attention U-Net model is used for segmentation, and architectures consisting of four CNNs and four ViTs were investigated for classification. Methods like Gradient-weighted Class Activation Mapping plus plus (Grad-CAM++) and Layer-wise Relevance Propagation (LRP) provide explainability by identifying crucial areas influencing model decisions.

Results:

The results support the conclusion that ViTs are outstanding in identifying lung disorders. Attention U-Net obtained a Dice Coefficient of 98.54% and a Jaccard Index of 97.12%. ViTs outperformed CNNs in classification tasks by 9.26%, reaching an accuracy of 98.52% with MobileViT. An 8.3% increase in accuracy was seen while moving from raw data classification to segmented image classification. Techniques like Grad-CAM++ and LRP provided insights into the decision-making processes of the models.

Conclusions:

This study highlights the benefits of integrating Attention U-Net and ViTs for analyzing lung diseases, demonstrating their importance in clinical settings. Emphasizing explainability clarifies deep learning processes, enhancing confidence in AI solutions and perhaps enhancing clinical acceptance for improved healthcare results.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Diagnostics (Basel) Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Diagnostics (Basel) Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: Suiza