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Molecular Mechanisms of Temperature Tolerance Plasticity in an Arthropod.
Aagaard, Anne; Bechsgaard, Jesper; Sørensen, Jesper Givskov; Sandfeld, Tobias; Settepani, Virginia; Bird, Tharina L; Lund, Marie Braad; Malmos, Kirsten Gade; Falck-Rasmussen, Kasper; Darolti, Iulia; Nielsen, Kirstine Lykke; Johannsen, Mogens; Vosegaard, Thomas; Tregenza, Tom; Verhoeven, Koen J F; Mank, Judith E; Schramm, Andreas; Bilde, Trine.
Afiliación
  • Aagaard A; Section for Genetics, Ecology and Evolution, Centre for EcoGenetics, Department of Biology, Aarhus University, Aarhus C, Denmark.
  • Bechsgaard J; Section for Genetics, Ecology and Evolution, Centre for EcoGenetics, Department of Biology, Aarhus University, Aarhus C, Denmark.
  • Sørensen JG; Section for Genetics, Ecology and Evolution, Centre for EcoGenetics, Department of Biology, Aarhus University, Aarhus C, Denmark.
  • Sandfeld T; Section for Microbiology, Department of Biology, Aarhus University, Aarhus C, Denmark.
  • Settepani V; Section for Genetics, Ecology and Evolution, Centre for EcoGenetics, Department of Biology, Aarhus University, Aarhus C, Denmark.
  • Bird TL; General Entomology, DITSONG: National Museum of Natural History, Pretoria, South Africa.
  • Lund MB; Department of Zoology and Entomology, University of Pretoria, Pretoria, South Africa.
  • Malmos KG; Department of Arachnology and Myriapodology, National Museum of Namibia, Windhoek, Namibia.
  • Falck-Rasmussen K; Section for Microbiology, Department of Biology, Aarhus University, Aarhus C, Denmark.
  • Darolti I; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus C, Denmark.
  • Nielsen KL; Section for Genetics, Ecology and Evolution, Centre for EcoGenetics, Department of Biology, Aarhus University, Aarhus C, Denmark.
  • Johannsen M; Department of Zoology and Biodiversity Research Centre, University of British Columbia, Vancouver, British Columbia, Canada.
  • Vosegaard T; Department of Ecology and Evolution, University of Lausanne, Lausanne, Switzerland.
  • Tregenza T; Department of Forensic Medicine, Aarhus University, Aarhus N, Denmark.
  • Verhoeven KJF; Department of Forensic Medicine, Aarhus University, Aarhus N, Denmark.
  • Mank JE; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus C, Denmark.
  • Schramm A; Department of Chemistry, Aarhus University, Aarhus C, Denmark.
  • Bilde T; Centre for Ecology and Conservation, University of Exeter, Penryn Campus, Penryn TR109FE, UK.
Genome Biol Evol ; 16(8)2024 Aug 05.
Article en En | MEDLINE | ID: mdl-39058286
ABSTRACT
How species thrive in a wide range of environments is a major focus of evolutionary biology. For many species, limited genetic diversity or gene flow among habitats means that phenotypic plasticity must play an important role in their capacity to tolerate environmental heterogeneity and to colonize new habitats. However, we have a limited understanding of the molecular components that govern plasticity in ecologically relevant phenotypes. We examined this hypothesis in a spider species (Stegodyphus dumicola) with extremely low species-wide genetic diversity that nevertheless occupies a broad range of thermal environments. We determined phenotypic responses to temperature stress in individuals from four climatic zones using common garden acclimation experiments to disentangle phenotypic plasticity from genetic adaptations. Simultaneously, we created data sets on multiple molecular modalities the genome, the transcriptome, the methylome, the metabolome, and the bacterial microbiome to determine associations with phenotypic responses. Analyses of phenotypic and molecular associations reveal that acclimation responses in the transcriptome and metabolome correlate with patterns of phenotypic plasticity in temperature tolerance. Surprisingly, genes whose expression seemed to be involved in plasticity in temperature tolerance were generally highly methylated contradicting the idea that DNA methylation stabilizes gene expression. This suggests that the function of DNA methylation in invertebrates varies not only among species but also among genes. The bacterial microbiome was stable across the acclimation period; combined with our previous demonstrations that the microbiome is temporally stable in wild populations, this is convincing evidence that the microbiome does not facilitate plasticity in temperature tolerance. Our results suggest that population-specific variation in temperature tolerance among acclimation temperatures appears to result from the evolution of plasticity in mainly gene expression.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Metilación de ADN / Transcriptoma Límite: Animals Idioma: En Revista: Genome Biol Evol Asunto de la revista: BIOLOGIA / BIOLOGIA MOLECULAR Año: 2024 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Metilación de ADN / Transcriptoma Límite: Animals Idioma: En Revista: Genome Biol Evol Asunto de la revista: BIOLOGIA / BIOLOGIA MOLECULAR Año: 2024 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Reino Unido